The aim of this study was to evaluate the impact of white blood cell (WBC) counts at presentation on the achievement of deep molecular response.A total of 362 newly diagnosed chronic-phase chronic myeloid leukemia patients (CML-CP) receiving 400 mg/day imatinib were serially monitored for a median of 36 months (range 6-115).Patients showing an optimal response at 3, 6, and 12 months as defined ...

This paper discusses two applications of probing dense volumetric data for MR orthopedics and dynamic contrast enhanced MRI mammography. In order not to reduce the context information and to extract the essential part of the data, we apply Profile Flags. A Profile Flag is a 3D glyph for probing and annotating the volumetric data. The first application area deals with visualization of T2 profile...

Skeletal polyhedra and polygonal complexes in ordinary Euclidean 3-space are finite or infinite 3-periodic structures with interesting geometric, combinatorial and algebraic properties. They can be viewed as finite or infinite 3-periodic graphs (nets) equipped with additional structure imposed by the faces, allowed to be skew, zigzag or helical. A polyhedron or complex is regular if its geometr...

Following earlier work by Mechsner et al. (Nature 414 (2001) 69), the purpose of this experiment was to determine the perceptual and motoric contributions to bimanual coordination. Twenty right-handed, healthy, young adults performed continuous, horizontal, linear movements of both upper limbs at frequencies of 1.5 and 2.0 Hz. The goal was to control the spatial-temporal displacement of two fla...

An abstract polytope of rank n is said to be chiral if its automorphism group has precisely two orbits on the flags, such that adjacent flags belong to distinct orbits. The present paper describes a general method for deriving new finite chiral polytopes from old finite chiral polytopes of the same rank. In particular, the technique is used to construct many new examples in ranks 3, 4 and 5.