EPIDEMIOLOGY Vulvar cancer can be classified into two groups according to predisposing factors: the first type correlates with a HPV infection and occurs mostly in younger patients. The second group is not HPV associated and occurs often in elderly women without neoplastic epithelial disorders. HISTOLOGY Squamous cell carcinoma (SCC) is the most common malignant tumor of the vulva (95%). CL...

This is a new case of Merkel cell carcinoma of the vulva. It is a rare neuroendocrine carcinoma with an aggressive behavior. Because of its rarity in this location, it is not clear whether it behaves differently from the usual neuroendocrine carcinomas of the skin. A case of a 63-year-old patient with vulvar Merkel carcinoma is presented. The clinical presentation, microscopic and immunohistoch...

A 63-year-old woman who was complaining of epigastric pain and abdominal fullness underwent an upper gastrointestinal endoscopy, which revealed a bulge in the lesser curvature and anterior wall of the gastric body (●" Fig.1). A computed tomography (CT) scan and a sectorial endoscopic ultrasound (EUS) using an Olympus GF-UCT140-AL5 (Olympus America Inc., New York, USA) coupled to an ultrasound u...

Purpose: At present, there are no clear guidelines for the treatment of the patients with vulva carcinoma. The aim of this study was to examine our experience with laparoscopic inguinal lymphadenectomy in women with vulva cancer. Methods: From November 2010 to December 2013, 15 patients with vulvar carcinoma underwent laparoscopic inguinal lymphadenectomy following radical local vulvectomy or, ...

Objective: The purpose of this study is to understand the incidence, related factors, and the prognosis factors in order to avoid risk, proper method of diagnosis and treatment and reduce complications and provide the basis. Methods: 85 Vulvar cancer (VC) patients treated in our hospital from 2002.10 to 2012.10 were collected and analyzed by retrospective comparative methods. SPSS19.0 applicati...

To cite: Garg M, Sharma P, Gupta S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200180 DESCRIPTION We report a case of 30-year-old woman presented with giant, foul smelling ulcerated growth involving the vulva. The growth was involving the whole of labia majora, minora and adjacent skin associated with itching, bleeding and discharge (figure 1). The...

The rather rare vulvar cancer is almost always a squamous cell carcinoma that mostly develops from an underlying VIN or HPV infection. In addition, lichen sclerosus et atrophicans, immune deficiency, nicotine abuse or anogenital intraepithelial neoplasias may play a role in the pathogenesis. Surgical therapy aims at an R0 resection in the sense of a complete vulvectomy or a radical local excisi...

"Muir-Torre syndrome, a subtype of Lynch is rare genetic disorder. We present the case female patient with long family and personal history who was diagnosed numerous benign malignant tumours various histology, including some sebaceous features, beginning at age 41. The majority were cutaneous tumours, treated complete resection, but they frequently recurred. Visceral cancers included endocervi...

Vulvar cancer accounts for less than 1% of malignancies in women. Verrucous carcinoma of the vulva is a rare histological variation, comprising less than 1% of vulvar cancer cases. Although it is characterized as being locally invasive, the condition is not associated with metastatic spreading. Lesions present in the form of a verrucous, ulcerated, and bleeding tumor that can reach large dimens...

Vulvar cancers, which constitute 5% of all gynecologic cancers, are the fourth most common female genital cancers, preceded by uterine, ovarian and cervical cancers. The treatment methods employed for vulvar cancers have changed over the years, with previously applied radical surgical approaches, such as en bloc resection, being gradually suspended in favor of treatment approaches that require ...