Methods In this single blind cross-over study, young male and female subjects (n=5, three males, two females; age range 18-21) consumed 40 grams of either whey (Zero Carb SRO by VPX) or soy protein (Iso-Rich Soy by Jarrow Formulas). Subjects reported to the lab on separate days (with at least 2 days between testing sessions) and underwent 3 hours of resting metabolic rate (RMR) testing. The the...

Background We have recently reported that the dietary supplement Meltdown® (Vital Pharmaceuticals) increases plasma norepinephrine (NE), epinephrine (EPI), glycerol, and free fatty acids (FFA), as well as metabolic rate in healthy men [1]. However, in that investigation measurements ceased at 90 minutes post ingestion, with values for bloodborne variables peaking at this time. It was the purpos...

We report the complete nucleotide sequence of a human immunodeficiency virus type 2 (HIV-2) isolate from Guinea-Bissau (HIV-2CAM2). The genomic organization of HIV-2CAM2 is identical to that of other HIV-2 isolates but contains a stop codon in the pol gene. The deduced amino acid sequences of the viral proteins show variation of 20% in the gag, pol and vpx regions, and 25 to 45% in the tat, env...

Methods In a double-blind, placebo-controlled, cross-over design, participants underwent two testing sessions after consuming either the VPX Meltdown® or placebo supplement. Healthy male participants (n = 12) aged 18–35 rested for one hour while energy expenditure (EE), respiratory exchange ratio (RER), heart rate (HR), and blood pressure (B) were assessed in a fasted state. Subsequently, parti...

Nef is one of the five so-called auxiliary genes of primate lentiviruses, a group that also includes vif, vpr, vpu (in HIV-1 and SIVCPZ), and vpx (in HIV-2 and other SIV strains). Inactivating these genes does not completely prevent viral replication in cell culture (reviewed in (Cullen, 1998)), but studies conducted both in SIV-infected monkeys and in HIV-infected individuals have revealed tha...