This report presents a computer-animated model of the structures of accommodation based on new understanding of the anatomy of the zonular apparatus integrated with current understanding of the mechanism of accommodation. Analysis of this model suggests a new, consolidated theory of the mechanism of accommodation including a new theory of reciprocal zonular action. A three-dimensional animated ...

Clinically in both the congenital and the acquired ocular disease, there is an acute focal chorioretinitis having its active onset of recurrence between ages 11 and 40 years old. Lesions may be single, variable in size, and are usually posterior to the equator. There is exudation into the vitreous and flare and cells in the anterior chamber. Vitreous may detach from the retina, with hemispheric...

Here we report a case of a congenital, free-floating pigmented vitreous cyst in a child. A 12-year-old male was referred to the Ophthalmology Clinic for amblyopia on his left eye. Ophthalmologic examination revealed that the visual acuity was 20/20 in the right eye and 20/35 in the left eye. Findings of the anterior segment examination were normal. On dilated fundus examination, a free-floating...

BACKGROUND The high incidence of retinal detachment and its poor surgical prognosis in patients with Stickler syndrome are well known. However, the vitreoretinal relation to retinal detachment in this syndrome is uncertain. METHODS Vitreoretinal examination with a binocular indirect ophthalmoscope and a Goldmann three mirror contact lens was performed on identical twin boys with Stickler synd...

Retinal glia migrate to sites in the vitreous body and on the inner and outer surfaces of the retina during a wide variety of pathological processes. Using in vitro cultures of rat retinal glia, we have evaluated an extensive list of homogeneous, well-characterized growth factors as chemoattractants for these cells. Humoral growth factors, fibroblast growth factors, extracellular matrix protein...

A slit-lamp fluorophotometric method is presented that permits calculation of a blood-retinal barrier permeability to fluorescein (P) and a diffusion coefficient for fluorescein in the vitreous body (D). The calculations are performed by relating the time course of the free--not protein bound--fluorescein concentration in the bloodstream with the fluorescein concentration profile in the vitreou...