Virus-like particles are used to encapsulate drugs, imaging agents, enzymes, and other biologically active molecules in order to enhance their function. However, the size of most virus-like particles is inflexible, precluding the design of appropriately sized containers for different applications. Here, we describe a chromatographic selection for virus-like particle assembly. Using this selecti...

SUMMARY Virus-like particles were recently described in an ependymoblastoma of CS7BL/J mice. For characterization of these particles, the tumor was explanted into cell culture. This study reports the growth of these cells in culture and the persistence of virus-like particles in the cells for up to 5 months in culture. The particles correspond to intracyto plasmic A particles and extracellular ...

The filovirus Ebola causes hemorrhagic fever with 70-80% human mortality. High case-fatality rates, as well as known aerosol infectivity, make Ebola virus a potential global health threat and possible biological warfare agent. Development of an effective vaccine for use in natural outbreaks, response to biological attack, and protection of laboratory workers is a higher national priority than e...

Recombinant papillomavirus-like particles have recently been shown to be highly effective for the prevention of papillomavirus infections and associated tumors, and a virus-like particle-based vaccine against the most prevalent HPV causing genital infection in humans will be developed in the near future. Another use of these virus-like particles may lie in gene therapy and DNA immunization. We ...

this is a report of (wo cases of monosymptomatic hypochondriacal psychosis who were convinced of having acquired immunodeficiency syndrome. they bitterly criticised the incompetence of their medical advisers, on of always showed virus-like particles of acquired immunodeficiency syndrome organisms beneath their lip mucosa or penile skin. vie first case was advised to continue psychofytic compoun...