نتایج جستجو برای: virotherapy

تعداد نتایج: 1060  

Journal: :Small 2023

Oncolytic Virotherapies In article number 2206948, Ying Wu, Ning Li, Funan Liu, and co-workers provide a more advanced approach to cancer immunotherapy, i.e. the oncolytic virotherapy. viruses selectively replicate in tumor cells exert antitumor effects through direct oncolysis inducting immune responses, where antigens from lysing enhance immunity.

2016
Narayanasamy Badrinath Jeong Heo So Young Yoo

Oncolytic virotherapy, a type of nanomedicine in which oncolytic viruses (OVs) are used to selectively infect and lyse cancer cells, is an emerging field in cancer therapy. Some OVs exhibit a specific tropism for cancer cells, whereas others require genetic modification to enhance their binding with and entry into cancer cells. OVs both kill tumor cells and induce the host's immune response aga...

2016
Fang Huang Bin-Rong Wang Ye-Qing Wu Fan-Chao Wang Jian Zhang Yi-Gang Wang

Gastrointestinal cancer has been one of the five most commonly diagnosed and leading causes of cancer mortality over the past few decades. Great progress in traditional therapies has been made, which prolonged survival in patients with early cancer, yet tumor relapse and drug resistance still occurred, which is explained by the cancer stem cell (CSC) theory. Oncolytic virotherapy has attracted ...

2012
Eric Bartee Amy Meacham Elizabeth Wise Christopher R. Cogle Grant McFadden

Graft-versus-host disease (GVHD) is a potentially lethal clinical complication arising from the transfer of alloreactive T lymphocytes into immunocompromised recipients. Despite conventional methods of T cell depletion, GVHD remains a major challenge in allogeneic hematopoietic cell transplant. Here, we demonstrate a novel method of preventing GVHD by ex vivo treatment of primary human hematopo...

2012
Oliver Donnelly Richard Vile Hardev Pandha Kevin Harrington Alan Melcher

1 In contrast to most other cancer therapies, early research with oncolytic viruses (OV) tended to use direct or intratumoural routes of administration, initially motivated by concerns that the major limitation of intravenous delivery would be immune attack against the viruses, whether by complement, cytokine or most critically neutralising antibodies. Even in the absence of preformed circulati...

Journal: :Biochemistry and Biophysics Reports 2018

Journal: :Expert Opinion on Biological Therapy 2009

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