viral proteins

Abstract: Autophagy-related (Atg) gene-encoded proteins were originally described for their crucial role in macroautophagy, a catabolic pathway for cytoplasmic constituent degradation in lysosomes. Recently it has become clear that modules of this machinery can also be used to influence endo- and exocytosis. This mini review discusses how these alternative Atg functions support virus replicatio...

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Genotype and phenotype of COVID-19: Their roles in pathogenesis

ژورنال: زیست شناسی ایران 2020

, ,

COVID-19 is a novel coronavirus with an outbreak of unusual viral pneumonia in Wuhan, China, and then pandemic. Based on its phylogenetic relationships and genomic structures the COVID-19 belongs to genera Betacoronavirus. Human Betacoronaviruses (SARS-CoV-2, SARS-CoV, and MERS-CoV) have many similarities, but also have differences in their genomic and phenotypic structure that can influence th...

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Different protein expression systems can influence the direction of the immune responses against HCV core protein in animal model

Journal: Vaccine Research 2015

A Bolhassani , N Davoudi , Sh Irani, SM Mirnurollahi ,

Introduction: Hepatitis C virus (HCV) infection is a major public health problem which influences about 170 million people worldwide. Different types of vaccines have been designed using HCV structural proteins to control the viral infection. The core nucleocapsid protein is one of the most conserved proteins and a desirable target for HCV vaccines, especially the protein-based vaccines. In cur...

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Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Journal: :Journal of Visualized Experiments 2017

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