01-P007 Characterising microRNA expression and function during embryonic gonadal development Stephanie Bannister, Henk Buermans, Ivano Broz, Mark Tizard, Timothy Doran, Andrew Sinclair, Craig Smith Livestock Industries, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australian Animal Health Laboratory, Geelong, Vic., Australia Center for Human and Clinical Genetics, Leide...

Eleanor C Saunders, David P De Souza, James I MacRae, Vladimir A Likic’ & Malcolm J McConville 1 Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, 30 Flemington Road, Parkville, VIC 3010 2 Metabolomics Australia, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, 30 Flemington Road, Pa...

IMPROVING EFFICIENCY OF SERVICEORIENTED CONTEXT-DRIVEN SOFTWARE AGENTS Kutila Gunasekera a , Seng Wai Loke b , Arkady Zaslavsky c & Shonali Krishnaswamy a a Faculty of Information Technology, Monash University, Caulfield East, VIC, Australia b Department of Computer Science & Computer Engineering, La Trobe University, Bundoora, VIC, Australia c Faculty of Information Technology, Monash Universi...

01-P007 Characterising microRNA expression and function during embryonic gonadal development Stephanie Bannister, Henk Buermans, Ivano Broz, Mark Tizard, Timothy Doran, Andrew Sinclair, Craig Smith Livestock Industries, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australian Animal Health Laboratory, Geelong, Vic., Australia Center for Human and Clinical Genetics, Leide...

The vic two-component signal transduction system of Streptococcus pneumoniae is essential for growth. The vic operon comprises three genes encoding the following: VicR, a response regulator of the OmpR family; VicK, its cognate histidine kinase; and VicX, a putative protein sharing 55% identity to the predicted product (YycJ) of an open reading frame in the Bacillus subtilis genome. We show tha...

Much remains to be discovered about the etiology of heart valve disease and the molecular level mechanisms that drive it. The MAPK/ERK pathway influences calcification in many cell types and has been linked to the expression of a contractile phenotype in valvular interstitial cells (VICs). However, a direct correlation between MAPK/ERK pathway activity and VIC calcification has not been previou...

Department of Pharmacy Practice, Faculty of Pharmacy, Monash University, Melbourne, VIC. Johnson George, MPharm, PhD Scholar; David C M Kong, MPharm PhD, Lecturer; and Senior Pharmacist, The Alfred, Melbourne, VIC; Kay Stewart, BPharm(Hons), PhD, Senior Lecturer. Ambulatory and Community Services, The Alfred, Melbourne, VIC. Lisa L Ioannides-Demos, BPharm, PhD, Senior Research Scientist; and Re...

This paper addresses the effectiveness of auctions and legal unbundling as regulatory measures to tender a vertically integrated industry more competitive. Specifically, I analyze if implementing auctions and legal unbundling can counter market power in an industry where a Vertically Integrated Corporation (VIC) has a monopoly position in an essential, scarce upstream activity and also owns one...

Isocitrate lyase (ICL, types 1 and 2) is the first enzyme of the glyoxylate shunt, an essential pathway for Mycobacterium tuberculosis (Mtb) during the persistent phase of human TB infection. Here, we report 2-vinyl-d-isocitrate (2-VIC) as a mechanism-based inactivator of Mtb ICL1 and ICL2. The enzyme-catalyzed retro-aldol cleavage of 2-VIC unmasks a Michael substrate, 2-vinylglyoxylate, which ...

For a low-power wireless communication, a fast-Fourier-transform (FFT) LSI for an orthogonal frequency division multiplexing (OFDM) system has been implemented with current-mode circuits. In this current-mode OFDM system, a voltage-current converter (VIC) should be designed with an operating frequency of more than 40 MHz, because the frequency bandwidth of the OFDM signal is recommended as 20 M...