OBJECTIVE To report an unusual lateral medullary stroke (LMS) associated with transient unidirectional horizontal, nystagmus, and decreased horizontal vestibulo-ocular reflex (h-VOR) gain that mimicked a peripheral vestibulopathy. MRI suggested involvement of caudal medial vestibular nucleus (MVN); however, the rapid resolution of the nystagmus and improved h-VOR gain favored transient ischemia...

Laboratory studies have suggested that the preferred cadence of walking is approximately 120 steps/min, and the vertical acceleration of the head exhibits a dominant peak at this step frequency (2 Hz). These studies have been limited to short periods of walking along a predetermined path or on a treadmill, and whether such a highly tuned frequency of movement can be generalized to all forms of ...

Sensory circuits in the dorsal spinal cord integrate and transmit multiple cutaneous sensory modalities including the sense of light touch. Here, we identify a population of excitatory interneurons (INs) in the dorsal horn that are important for transmitting innocuous light touch sensation. These neurons express the ROR alpha (RORα) nuclear orphan receptor and are selectively innervated by cuta...

The diagnosis of patient disorders in modern neurootological centers has to include not only history and examination but objective and quantitative tests. In this study, we stress the importance of a short but significant test used to study vestibular function--the vestibular test of balance. The most common and widespread technique used to evaluate a patient's equilibrium in static condition i...

foreign bodies in lower urinary tract may present in a different number of ways. we report four cases of such unusual presentation. physical examination and plain radiograph was sufficient enough to confirm our diagnosis in all cases. the cases belonged to different age groups and three out of four cases were managed by open surgical approach. one foreign body was removed using cystoscope. prom...

Ex vivo gene therapy, utilizing modified fibroblasts that deliver BDNF or NT-3 to the acutely injured spinal cord, has been shown to elicit regeneration and recovery of function in the adult rat. Delayed grafting into the injured spinal cord is of great clinical interest as a model for treatment of chronic injury but may pose additional obstacles that are not present after acute injury, such as...