The management of human African trypanosomiasis (HAT) is constrained by lack of simple-to-use diagnostic, staging, and treatment tools. The search for novel biomarkers is, therefore, essential in the fight against HAT. The current study aimed at investigating the potential of IL-6 as an adjunct parameter for HAT stage determination in vervet monkey model. Four adult vervet monkeys (Chlorocebus ...

The results of an international comparative study of the neurovirulence of oral poliomyelitis vaccines in three species of Old World Monkeys, viz. Macacus irus (cynomolgus), M. mulalla (rhesus) and Cercopithecus aelhiops (vervet) are pre3ented. The greate~t sensitivity to Sabin poliovaccine types 1 and IIr was shown by cynomolgus monkeys, followed by rhesus and vervet monkeys, whilst vervet mon...

In species that live in stable groups, successful management of time budget (i.e., the proportion involved different behaviours) and social relationships has been proposed to be a key variable affecting individual fitness. Such is limited by constraints, which are group size season dependancy. However, link between constraints grooming patterns as means service never studied experimentally. Her...

BACKGROUND Understanding the evolutionary origins of a phenotype requires understanding the relationship between ontogenetic and phylogenetic processes. Human infants have been shown to undergo a process of perceptual narrowing during their first year of life, whereby their intersensory ability to match the faces and voices of another species declines as they get older. We investigated the evol...

CI-744 is a new agent for chemical restraint and surgical anesthesia in animals, consisting of equal parts by weight of the cataleptoid agent tiletamine-HCl and the tranquilizer zolazepam-HCl. We have used it in the intramuscular dose of five to ten milligrams per kilogram to anesthetize 110 cynomolgus and 10 vervet monkeys a total of 1,500 times for various ophthalmological procedures. At thes...

An experimental luting resin became available for evaluation o f its pulpal irritation potential. The ma­ terial is a high molecular weight urethane-di-methacrylate which does not require a thinning mo­ nomer such as tri-ethylene-glycol-di-methacrylate (TEGMA). In each o f 24 anaesthetized adult vervet monkeys labial cavities were cut in each o f the 8 inci­ sor teeth. In each monkey 2 randomly...

While hippocampal connectivity is essential to normal memory function, our knowledge of human hippocampal circuitry is largely inferred from animal studies. Using polarized light microscopy at 1.3 µm resolution, we have directly visualized the 3D course of key medial temporal pathways in 3 ex vivo human hemispheres and 2 ex vivo vervet monkey hemispheres. The multiple components of the perforan...