BACKGROUND Takotsubo cardiomyopathy is an increasingly recognized acute heart failure syndrome precipitated by intense emotional stress. Although there is an apparent rapid and spontaneous recovery of left ventricular ejection fraction, the long-term clinical and functional consequences of takotsubo cardiomyopathy are ill-defined. METHODS In an observational case-control study, we recruited 3...

Takotsubo cardiomyopathy is a reversible form of left ventricular dysfunction with an apparently benign natural history after left ventricular recovery. Rarely there are complications such as arrhythmias and apical thrombus. We describe a case of takotsubo cardiomyopathy complicated with apical thrombus and persistent complete atrioventricular block after improvement of left ventricular wall mo...

We present a unique case of a patient, aged 80 years, who presented with delirium and takotsubo syndrome. Also known as "broken heart syndrome" because it often originates following an emotional stress, takotsubo syndrome may be difficult to distinguish from myocardial infarction because of similar symptoms and demographics. However, the distinction of these opposing diagnoses is significant be...

Apical ballooning is a cardiac syndrome (Takotsubo Cardiomyopathy) described as a typical form of acute transient left ventricular dysfunction. While its onset has often been associated with emotionally or physically stressful situations, it has an overall favorable prognosis. We describe here a case of transient apical ballooning following permanent pacemaker implantation.

Takotsubo cardiomyopathy (TCM) is a medical condition characterized by a transient left ventricular apical dysfunction with unknown etiology. The clinical presentation mimics acute myocardial syndrome in the absence of obstructive coronary artery disease. The association between acute pancreatitis and TCM, however, is rarely reported in the literature. To date, no cases of TCM resulting from th...

I have some thoughts about the report by Srivastava et al, published online ahead of print on 17 August, 2015, in the Journal, about a 14-year-old boy who suffered two Takotsubo syndrome attacks 6 months apart, triggered by status epilepticus. Regarding the possible pathophysiology of Takotsubo syndrome, the authors refer to an “exaggerated sympathetic nervous system response to catecholamines”...

Although originally considered to be uncommon, Takotsubo cardiomyopathy is becoming increasingly visible, annually comprising an increasing portion of suspected diagnoses of acute coronary syndrome. This condition is characterized by reversible left ventricular akinesis without significant coronary artery obstruction. This case study presents five patients diagnosed with Takotsubo cardiomyopath...

DESCRIPTION This 55-year-old lady became acutely hypotensive during induction of anaesthesia with fentanyl, propofol and atracurium for elective cholecystectomy. She developed anterior ST segment elevation and runs of ventricular tachycardia. The operation was abandoned, and subsequent ECGs showed a deep T-wave inversion in the anterolateral leads (figure 1). Her troponin was elevated. The pati...

Transient left ventricular apical ballooning is a newly defined syndrome characterized by sudden onset of chest symptoms, electrocardiographic changes characteristic of myocardial ischemia, transient left ventricular dysfunction-particularly in the apical region, low-grade troponin elevation, and no significant coronary stenosis by angiogram. This syndrome is also referred to as Takotsubo cardi...

OBJECTIVES The present study was designed to delineate and compare the clinical characteristics of patients with apical and non-apical takotsubo syndrome in a high-volume U.S. hospital. BACKGROUND A comparison between apical and non-apical variants of the "broken heart," or takotsubo syndrome, has not been performed in the United States. METHODS From 2004 through 2007, patients with takotsu...