AIM: To evaluate the clinical efficacy and systemic safety profile of conbercept in practice on vascular endothelial growth factor (VEGF)-A, VEGF-B, placental (PLGF) levels after intravitreal injections for neovascular age-related macular degeneration (AMD). METHODS: Thirty-five patients (35 eyes) with AMD received treatment pro re nata protocol. Best-corrected visual acuity (BCVA) central reti...

Abstract We evaluated changes in the complement system resulting from anti-vascular endothelial growth factor (VEGF) eyes with age-related choroidal neovascularization (CNV) including neovascular macular degeneration, pachychoroid neovasculopathy, and polypoidal neovasculopathy. measured concentrations of activation products (C3a, C4a), VEGF, monocyte chemotactic protein-1 aqueous humor during ...

background: crimean-congo hemorrhagic fever (cchf) is a disease characterized by serious course, including acute viral fever, ecchymosis, thrombocytopenia, liver dysfunction and high rate of mortality. hypoxia inducible factor-1α (hif-1α) and vascular endothelial growth factor-a (vegf-a) play an important role both in the inflamma­tory process and plasma leakage. the aim of this study was to de...

some important compatibility that occur with exercise is increase of the capillary density or angiogenesis. vascular endothelial growth factor (vegf) have mitogen role for endothelial cells and consider an important intermediary angiogenesis process. the purpose of this study was comparing the effect of two type of physical activity on response of serum vegf-a in non-athlete men. for this aim 1...

Objective(s):Although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hUCM) transplantation post myocardial infarction (MI), but this stem cell resource has no potential to induce angiogenesis. In order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hUCM ...

Background: Psoriasis is a chronic disease with multiple biochemical and vascular abnormalities. Several studies have evaluated circulating levels of vascular endothelial growth factor (VEGF) in psoriasis, but none of them evaluated it after reaching a PASI-75 response, as a practical treatment goal. The aim of this study was to evaluate serum levels of VEGF in moderate to severe psoriatic pati...