Type 2 diabetes (T2D) has become a major problem around the world. Current research has linked a high dietary fibre (DF)intake with a number of health benefits and possible prevention of T2D. One proposed mechanism is via short chain fatty acids (SCFA), which are produced from fermentation of DF in the colon by the microflora. A high DF intake will cause higher concentration of SCFA in the bloo...

Abstract Metabolites produced by microbial fermentation in the human intestine, especially short-chain fatty acids (SCFAs), are known to play important roles colonic and systemic health. Our aim here was advance our understanding of how why their concentrations proportions vary between individuals. We have analysed faecal from 10 volunteer studies, involving 163 subjects, conducted at Rowett In...

objective: : polycystic ovary syndrome (pcos) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. in this study, the effect of pcos induction was studied using estradiol valerate. materials and methods: ad...

A double-blind, randomized clinical study was conducted to compare the efficacy and tolerability of twice-daily topical calcipotriol treatment with a combination treatment of calcipotriol once a day in the morning and diflucortolone valerate in the evening. Sixty-three patients with a clinical diagnosis of chronic plaque psoriasis and comparable psoriatic lesions on both sides of the body were ...

4-(4′-ethoxyphenylazo) phenyl valerate (EPPV) is a nematic liquid crystal, which shows a nematic mesophase at 352 K and becomes an isotropic melt at 401 K. A theoretical study of the molecular ordering has been carried out on the basis of intermolecular interaction energy calculations. The CNDO/2 method has been employed to compute the net atomic charge and atomic dipole components at each atom...

Previous studies suggested that estrogen plays a role in cognitive function by modulating the cholinergic transmission. However, most of the studies dealing with this subject have been conducted using ovariectomized rats. In the present study we evaluated the effects of physiological and supra-physiological variation of estrogen levels on scopolamine-induced amnesia in gonadally intact female r...

in this study, microspheres containing estradiol valerate were prepared by solvent evaporation method using poly (glycolide-co-lactide) (plga 50:50) and poly (lactide). the effect of different process variables such as polymer type, drugpolymer ratio, stirring rate, volume of internal phase and temperature of external phase on the morphology, particle size distribution, encapsulation efficiency...