Purpose. To explore the effects of SiJunZiTang (SJZT) on central neurotransmitters and the inhibition of HCl hypersecretion, along with the role of the vagus nerve. From this, the effects of SJZT and its constituent ingredients on inhibiting stress-induced peptic ulcers will be determined. Methods. Methods used to determine SJZT's effectiveness included (1) measuring the antipeptic ulcer effect...

The authors present experiments demonstrating that the hypertension produced by the stimulation of the central end of the vagus nerve is brought about by the appearance of a pressor substance in the circulating blood. The results of these experiments show that such a substance does not come from any gland nor from the central nervous system. The observed facts indicate that its origin is the ar...

Unit activity evoked by electrical stimulation of the aortic and vagus nerves was recorded in the dorsal motor nucleus and nucleus solitarius of unanesthetized rabbits. Cardioinhibitory cells which showed antidromic activation to stimulation of the vagus nerve and synaptic activation to stimulation of the aortic nerve were localized in lateral dorsal motor nucleus 0.5-0.8 mm anterior of the obe...

Neural reflexes support homeostasis by modulating the function of organ systems. Recent advances in neuroscience and immunology have revealed that neural reflexes also regulate the immune system. Activation of the vagus nerve modulates leukocyte cytokine production and alleviates experimental shock and autoimmune disease, and recent data have suggested that vagus nerve stimulation can improve s...

Hosoi, Toru, Yasunobu Okuma, and Yasuyuki Nomura. Electrical stimulation of afferent vagus nerve induces IL-1b expression in the brain and activates HPA axis. Am J Physiol Regulatory Integrative Comp Physiol 279: R141–R147, 2000.—Possible roles of the afferent vagus nerve in regulation of interleukin (IL)-1b expression in the brain and hypothalamic-pituitary-adrenal (HPA) axis were examined in ...

Article history: Received: 17 November, 2015 Revised: 6 December, 2015 Accepted: 19 December, 2015 Published online: 20 December, 2015 Background and Aim: Analysis of heart rate variability (HRV) has recently become the playing field of mathematicians and physicists, losing its relation to physiology and the clinic. To set the record straight, a set of animal experiments is presented here, whic...

The effect of temperature on the action of the vagus nerve on the heart was studied in the toad Bufo marinus. Experiments were performed on two groups of toads, in one the heart was perfused at a constant rate with oxygenated Ringer's solution and in the other the circulation was left intact. In all toads there was a linear relationship between pulse interval (PI) and the frequency of vagal sti...