Primary vaginal cancer represents only 1% to 2% of malignant neoplasm of the female genital tract. Here, we report a 68-year-old woman who showed a vaginal tumor extending to urethra and clitoris, a 10 cm-sized mass in left adnexa and multiple metastases in lung and liver. Vaginal biopsy showed squamous cell carcinoma of vagina and she was diagnosed as International Federation of Gynecology and...

OBJECTIVES We performed a phase I trial to assess the safety and tolerance of a Lactobacillus vaginal suppository for prevention of recurrent UTI. METHODS Premenopausal women with a history of recurrent UTI were randomized to use L. crispatus CTV-05 or placebo vaginal suppositories daily for five days. RESULTS 30 women were randomized (15 to L. crispatus CTV-05). No severe adverse events oc...

A 64-year-old female was admitted from the emergency department after experiencing profuse vaginal bleeding while on anticoagulation for atrial fibrillation. She had previously experienced intermittent vaginal spotting. Her medical history was also significant for cervical cancer treated with external beam radiation therapy, breast cancer treated with lumpectomy, hypertension, urinary incontine...

Up to half of all postmenopausal women will experience changes in the genitourinary tract induced by the hypoestrogenic state, collectively known as vaginal atrophy. Vaginally administered local estrogen therapy (LET) is the standard of care for symptoms of vaginal atrophy that do not respond to nonhormonal interventions. Several LET formulations are available, and choice of therapy is based la...

introduction urinary tract infection is a common disease in the general population. however, in patients with frequent urinary tract infection, it is important to determine any treatable cause to avoid recurrence. case presentation herlyn-werner-wunderlich syndrome or ohvira syndrome is a very rare congenital anomaly with uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. ...

Background:Spontaneous bladder rupture is a rare condition, and almost all the reported cases in the world have been preceded by bladder dysfunction, radiotherapy, urinary tract obstruction, pelvic surgery, inflammation, and malignancy. Case report: In this study, we present the case of a 39-year-old woman (G: 4, P: 1, Ab: 2) who was in week 38 of pregnancy and attended our hospital with the on...

A 17 1⁄2-yr-old female is referred to the multidisciplinary pediatric pelvic reconstructive surgery program for consultation. The local gynecologist was uncomfortable with management of vaginal agenesis. She had a normal 16,XX karyotype. An MRI showed normal kidneys and a normal urinary tract. The MRI suggested a midline uterine structure. An exam under anesthesia and laparoscopy revealed a 1-c...

BACKGROUND: Reproductive tract sarcomas metastasizing to the breast are uncommon. To our knowledge, metastasis of vaginal leiomyosarcoma to the breast has not been previously reported in the literature. CASE REPORT: We present the first report of a FIGO stage IV primary vaginal leiomyosarcoma with metastases to the lung and left breast. Treatment included neoadjuvant chemotherapy followed by s...

Vulvovaginal candidiasis (VVC), caused by Candida species, is a fungal infection of the lower female genital tract that affects approximately 75% of otherwise healthy women during their reproductive years. Predisposing factors include antibiotic usage, uncontrolled diabetes and disturbance in reproductive hormone levels due to pregnancy, oral contraceptives or hormone replacement therapies. Rec...

background: group b streptococcus (gbs) colonizes the gastrointestinal and genitourinary tract of 10-40% of pregnant women and it is a major cause of neonatal morbidity and mortality. objective: this study was to evaluate whether vaginal gbs culture results alter after digital vaginal examination or not. antibiotic resistance pattern of this specie has been also assessed. materials and methods:...