نتایج جستجو برای: vaccine efficacy

تعداد نتایج: 405191  

Journal: :The New England journal of medicine 2012
Robert B Belshe Peter A Leone David I Bernstein Anna Wald Myron J Levin Jack T Stapleton Iris Gorfinkel Rhoda L Ashley Morrow Marian G Ewell Abbie Stokes-Riner Gary Dubin Thomas C Heineman Joann M Schulte Carolyn D Deal

BACKGROUND Two previous studies of a herpes simplex virus type 2 (HSV-2) subunit vaccine containing glycoprotein D in HSV-discordant couples revealed 73% and 74% efficacy against genital disease in women who were negative for both HSV type 1 (HSV-1) and HSV-2 antibodies. Efficacy was not observed in men or HSV-1 seropositive women. METHODS We conducted a randomized, double-blind efficacy fiel...

BACKGROUND: The control of coccidiosis in poultry industryis dominated by prophylactic chemotherapy; however,drug resistance is a serious problem. Alternative control methodssuch as vaccination have been accepted as a practical method forcontrolling coccidiosis in chickens. Considering the immunologicalvariation of Eimeria strains, the efficacy of live coccidiosisvaccines may be compromised. OB...

Journal: :Human vaccines 2011
Leia Wren Stephen J Kent

The partial efficacy of the recent HIV-1 vaccine trial in Thailand has rejuvenated the HIV vaccine field. There are now clear opportunities to dissect the potential correlates of protection against HIV-1. Comparisons of three major HIV-1 vaccine strategies used in human efficacy trials to date highlight a possible role for antibody-dependent cellular cytotoxicty (ADCC), rather than cytotoxic T ...

2016
Katsiaryna Holl Christophe Sauboin Emanuele Amodio Paolo Bonanni Giovanni Gabutti

BACKGROUND Varicella is a highly infectious disease with a significant public health and economic burden, which can be prevented with childhood routine varicella vaccination. Vaccination strategies differ by country. Some factors are known to play an important role (number of doses, coverage, dosing interval, efficacy and catch-up programmes), however, their relative impact on the reduction of ...

Journal: :International Journal of Applied Pharmaceutics 2022

Objective: To Evaluate intensively patients taking Sinovac-CoronaVac vaccine for the side effects and effectiveness in preventing COVID infection.
 Methods: This is a prospective crossectional study using convenience sampling all Indonesian populations who received full dose of vaccine.
 Results: The efficacy safety 96.8%. factors that influence are with Age, BMI Gender p-value<0.0...

2013
Matthew B. Laurens Mahamadou A. Thera Drissa Coulibaly Amed Ouattara Abdoulaye K. Kone Ando B. Guindo Karim Traore Idrissa Traore Bourema Kouriba Dapa A. Diallo Issa Diarra Modibo Daou Amagana Dolo Youssouf Tolo Mahamadou S. Sissoko Amadou Niangaly Mady Sissoko Shannon Takala-Harrison Kirsten E. Lyke Yukun Wu William C. Blackwelder Olivier Godeaux Johan Vekemans Marie-Claude Dubois W. Ripley Ballou Joe Cohen Tina Dube Lorraine Soisson Carter L. Diggs Brent House Jason W. Bennett David E. Lanar Sheetij Dutta D. Gray Heppner Christopher V. Plowe Ogobara K. Doumbo

BACKGROUND The FMP2.1/AS02A candidate malaria vaccine was tested in a Phase 2 study in Mali. Based on results from the first eight months of follow-up, the vaccine appeared well-tolerated and immunogenic. It had no significant efficacy based on the primary endpoint, clinical malaria, but marginal efficacy against clinical malaria in secondary analyses, and high allele-specific efficacy. Extende...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه زنجان - دانشکده علوم انسانی 1390

the main purpose of this study was to investigate any relationship between high school efl teachers metaphorical understandings of their role in class and their self-efficacy beliefs. teachers metaphors were elicited through two different prompts: one picturing what they believed a language teacher should be like in class, and the other demonstrating what they are actually like in class; such...

Journal: :The Journal of infectious diseases 2014
Linda C Lambert

The significant burden of disease due to pertussis, which predominantly affects newborns during their first few months of life, was substantially decreased following the introduction of inactivated whole-bacterial-cell vaccines in the middle of the 20th century. Although these vaccines were effective in reducing the incidence of pertussis in the countries that implemented their widespread use, ...

The human papillomavirus (HPV) is a highly contagious and prevalent virus that is primarily sexually transmitted. The Gardasil® quadrivalent vaccine, the Cevarix® bivalent vaccine and the Gardasil® 9 nonavalent vaccine were developed to prevent the spread of HPV as well as the incidence of its associated diseases. The aim of this mini-review is to critically analyze the safety and efficacy of b...

Journal: :The New England journal of medicine 2015
Himal Lal Anthony L Cunningham Olivier Godeaux Roman Chlibek Javier Diez-Domingo Shinn-Jang Hwang Myron J Levin Janet E McElhaney Airi Poder Joan Puig-Barberà Timo Vesikari Daisuke Watanabe Lily Weckx Toufik Zahaf Thomas C Heineman

BACKGROUND In previous phase 1-2 clinical trials involving older adults, a subunit vaccine containing varicella-zoster virus glycoprotein E and the AS01B adjuvant system (called HZ/su) had a clinically acceptable safety profile and elicited a robust immune response. METHODS We conducted a randomized, placebo-controlled, phase 3 study in 18 countries to evaluate the efficacy and safety of HZ/s...

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