The acidic glycosphingolipid composition of human uterine endometrial adenocarcinoma was compared with those of normal uterine endometrium at the proliferative and the secretory phases. Upon chemical composition analysis, no significant transformation-associated change of these glycolipids was observed. However, when cancer cells from the patients with human uterine endometrial adenocarcinoma w...

Herein we report the clinical, histopathological, and molecular features of a cancer syndrome with predisposition to uterine leiomyomas and papillary renal cell carcinoma. The studied kindred included 11 family members with uterine leiomyomas and two with uterine leiomyosarcoma. Seven individuals had a history of cutaneous nodules, two of which were confirmed to be cutaneous leiomyomatosis. The...

For women, gynaecological or obstetrical disorders are second to disc prolapse as the most common cause of sciatica. As not many effective conventional treatments can be found for sciatica following uterine cancer, patients may seek assistance from complementary and alternative medicine. Here, we present a case of a woman with severe and chronic sciatica secondary to uterine cancer who experien...

A patient who has multiple lung masses with a history of malignancy in organs other than the lung is more likely to be diagnosed with metastatic rather than primary lung cancer. Rarely, metastatic cancer can coexist with primary. We experienced a case of concurrent diagnosis of primary small cell lung cancer and pulmonary metastasis of uterine malignant mixed Müllerian tumor (MMMT). The patient...

Uterine cervical cancer is caused, mostly, by persistent infection with some types of Human Papilloma Virus (HPV), with types 16 and 18 showing higher risk for developing the disease. Because there is no effective drug treatment, early diagnosis of cervical cancer is very important for prognosis. The objective of this paper is to review the current immunohistochemical markers used in diagnosis,...

Obstructive jaundice as an initial manifestation of uterine cancer is extremely rare. We present a case of a 72-year-old female who presented with obstructive jaundice, supposedly for pancreatic cancer. After detailed diagnostic investigation, the cause of the jaundice was attributed to a metastatic compression of the common bile duct, from the primary neoplasm of the uterus. This case highligh...

M e t h o d s Design: Randomized controlled trial. Allocation: Concealed.* Blinding: Blinded (clinicians, participants, and outcome assessors).* Follow-up period: Mean 3.9 years. Setting: Nearly 200 clinical centers in North America. Participants: 19747 postmenopausal women ≥ 35 years of age (mean 59 y, 93% white) whose 5-year predicted breast cancer risk was ≥ 1.66% (mean 4.03%) based on the G...

Cytopathology is now regarded as an important tool for detecting cancer, especially uterine cervical cancer. There was, however, a hard way to acquire the current status. This technique, the diagnosis of cancer by light microscopic examination of exfoliated cells, was first established by Dr. Papanicolaou in the 1940's. For spreading this technique and acknowledgement of this clinical field by ...

Lymphoepithelioma-like carcinoma occurring in the reproductive organs is a rare variant of squamous cell carcinoma, and this tumor of the uterine cervix accounts for 0.7% of all primary cervical uterine neoplasms. Associations with Epstein-Barr virus (EBV) and human papilloma virus (HPV) have been demonstrated in some studies. Some investigators suggested that EBV has an important role in the i...