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Aims Thiamine is reabsorbed by the transporters THTR1 and THTR2 (encoded by SLC19A2 and SLC19A3 genes, respectively) in kidney proximal tubule. Decreased plasmatic thiamine concentrations resulting from increased renal clearance was demonstrated in type 2 and type 1 diabetes (T1D) patients. Increased thiamine urinary excretion is an independent risk factor for renal function decline in T1D pati...

BACKGROUND AND OBJECTIVES Urine sediment interpretation is frequently used in the evaluation of patients with kidney disease. There has been no systematic evaluation of the reliability of this diagnostic maneuver. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Digital photographs of urine sediment images were acquired from 165 consecutive patients being evaluated by the nephrology consultation...

Survival and settlement of Pocillopora damicornis larvae on hard surfaces covered with fine (<63 µm) terrigenous red clay was measured in laboratory Petri dishes. The dishes were prepared with sediment films of various thicknesses covering the bottoms. Coral larvae were incubated in the dishes for two weeks and the percent that settled on the bottom was determined. There was a statistically sig...

BACKGROUND Sorption and biodegradation are the primary processes of organic pollution remediation in aquatic and soil/sediment environments. While researchers have substantially reported their findings regarding these processes, little attention has been given to description of experimental apparatus. This technical paper aims to present the development and detailed design of a fixed-bed column...

The vast marine deep biosphere consists of microbial habitats within sediment, pore waters, upper basaltic crust and the fluids that circulate throughout it. A wide range of temperature, pressure, pH, and electron donor and acceptor conditions exists-all of which can combine to affect carbon and nutrient cycling and result in gradients on spatial scales ranging from millimeters to kilometers. D...

Accumulations of sediment beneath the Antarctic Ice Sheet contain a range of physical and chemical proxies with the potential to document changes in ice sheet history and to identify and characterize life in subglacial settings. Retrieving subglacial sediments and sediment cores presents several unique challenges to existing technologies. This paper briefly reviews the history of sediment sampl...

BACKGROUND Evidence indicates that microRNAs (miRNA) play a role in the pathogenesis of chronic kidney diseases (CKD). We explored the possibility of using urinary miRNA as non-invasive biomarkers for CKD. METHODS We quantified miRNA expression in urinary sediment of 56 CKD patients who underwent kidney biopsy. Patients were followed for 16.2 ± 15.5 months. RESULTS Patients with diabetic gl...

Neutrophil gelatinase-associated lipocalin (NGAL) is a neutrophil-derived protein whose concentration increases in plasma and urine with ongoing renal damage. Urinary leucocytes can be a potential source of urinary NGAL. The aim of this study is to investigate the effects of urinary neutrophil count and other urinary parameters on urinary NGAL values in urine with negative culture. Urinalysis, ...