BACKGROUND Diarrhea is a frequently occurring adverse event during treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR TKIs) and is mostly accompanied by abdominal cramps, flatulence and pyrosis. These complaints impair quality of life and lead to dose reductions and treatment interruptions. It is hypothesized that the diarrhea might be due to ischemia i...

INTRODUCTION Endoscopy is an invasive procedure and finding noninvasive alternative tools in detection of probable upper gastrointestinal (GI) tract injuries following caustic ingestion is an area of interest. The present study aimed to evaluate the screening performance characteristics of thoraco-abdominal computed tomography (CT) scan in this regard. METHODS This prospective cross sectional...

Endoscopic vacuum-assisted closure (VAC) is increasingly being used as a means of managing perforations or anastomotic leaks of the upper gastrointestinal (GI) tract. Published outcomes are favourable, with few mentions of complications or morbidity. We present a case in which the management of a gastric perforation with endoscopic vacuum therapy was complicated by cervical oesophageal perforat...

Colonic perforation caused by upper gastrointestinal (GI) endoscopy is extremely rare. A 69-year-old woman was referred to our hospital because of abdominal fullness. Colonoscopy could be performed only up to the hepatic flexure due to an elongated colon and residual stools. Because her symptoms improved, upper GI endoscopy was performed 11 days later. The patient developed severe abdominal pai...

S20 S ince the first successful surgery in 1941 (1), the survival of patients with esophageal atresia (EA) has improved greatly. Consequently, the follow-up of these patients has revealed gastrointestinal (GI) complications unrecognized 60 years ago, such as gastroesophageal reflux and esophagitis with their related consequences. Among these complications, 1 of the major concerns in long-term G...

Since its introduction in the 1950s, fiberoptic endoscopy has dramatically altered the scope and practice of gastrointestinal (GI) pathology. Whereas examination by rigid instruments was generally restricted to the proximal digestive foregut and distal 25 cm of the large bowel, fiberoptic endoscopy extended these limits considerably, which resulted in a greater volume of biopsies submitted to t...

background: selecting the best medication for upper gi endoscopy in children is a challenging issue. the goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (ugie) on children. methods: in this randomized clinical trial study conducted in amirkola children's hospital, 110 children were randomly assigned to oral or intravenous...

After the age of 65 years, iron deficiency anemia (IDA) requires the elimination of digestive neoplasia and is explored with upper and lower gastrointestinal (GI) endoscopy. However, such explorations are negative in 14% to 37% of patients. To further evaluate this issue, we evaluated the outcomes of patients aged over 65 years with endoscopy-negative IDA.We retrospectively analyzed the outcome...