Randomized experiments have been used to assist decisionmaking in many areas. They help people select the optimal treatment for the test population with certain statistical guarantee. However, subjects can show significant heterogeneity in response to treatments. The problem of customizing treatment assignment based on subject characteristics is known as uplift modeling, differential response a...

Understanding the uplift history and the evolution of high altitude plateaux is of major interest to a wide range of geoscientists and has implications for many disparate fields. Currently the majority of palaeoaltimetry proxies are based on detecting a physical change in climate in response to uplift, making the relationship between uplift and climate difficult to decipher. Furthermore, curren...

Recent geomorphic studies suggest that significant (∼1.5 km) late Cenozoic surface uplift occurred in the southern Sierra Nevada, a conclusion that is difficult to reconcile with recent stable-isotopic paleoaltimetry studies. Numerical modeling can play an important role in resolving this dispute. In this paper I use two models of bedrock channel erosion, the stream-power model and a sediment-f...

[1] Climate change indirectly alters the distribution of tectonic uplift at active orogens by modifying the action of surface processes, which in turn alters mountain topography. The impact of alpine glaciation on tectonic activity is explored here. The predictions of previous analytical, critical wedge models are compared with the output of a numerical model that explicitly couples rock uplift...

This paper presents new theoretical predictions of the undrained uplift capacity of deeply embedded inclined strip anchors in a soil stratum with a linear variation of strength with depth. Rigorous bounds on the theoretical uplift capacity are presented using upper and lower bound limit analysis. The effects of the strength gradient on the normalised uplift capacity and the predicted failure me...

BACKGROUND The findings of the Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT) study may be poorly generalisable to tiotropium use in clinical practice. METHODS An audit of 226 patients admitted to Wellington Hospital with a chronic obstructive pulmonary disease exacerbation determined the proportion of patients prescribed tiotropium on discharge that would have...

Evidence of long-term, late Cenozoic uplift, as well as strike-slip faulting, is revealed by topographic and geological features along the northern 500 km of the Dead Sea fault system (DSFS) – the transform boundary between the Arabian and African plates in the eastern Mediterranean region. Macro-geomorphic features are studied using a new, high-resolution (20 meter pixel) digital elevation mod...

Abstract Numerical simulation approaches have been widely applied to study mining induced subsidence, and they are potential methods the flooding uplift for abandoned mines. This paper gives an overview about different numerical simulate by underground mines, including three hydraulic conditions, considering both unconfined confined water conditions. Four basic schemes using 1-dimensional rock ...

As the potential for enhancement technologies migrates from the theoretical to the practical, a difficult and important decision will be imposed upon human civilization, namely the issue as to whether or not we are morally obligated to biologically enhance nonhuman animals and integrate them into human and posthuman society. Precedents for intra-species cultural uplift abound in human history, ...