نتایج جستجو برای: ultrasound sonothrombolysis

تعداد نتایج: 108724  

2016
Antonios N Pouliopoulos James J Choi

The introduction of microbubbles in focused ultrasound therapies has enabled a diverse range of non-invasive technologies: sonoporation to deliver drugs into cells, sonothrombolysis to dissolve blood clots, and blood-brain barrier opening to deliver drugs into the brain. Current methods for passively monitoring the microbubble dynamics responsible for these therapeutic effects can identify the ...

Journal: :Stroke 2008
Andrei V Alexandrov Robert Mikulik Marc Ribo Vijay K Sharma Annabelle Y Lao Georgios Tsivgoulis Rebecca M Sugg Andrew Barreto Paul Sierzenski Marc D Malkoff James C Grotta

BACKGROUND AND PURPOSE Ultrasound transiently expands perflutren-lipid microspheres (muS), transmitting energy momentum to surrounding fluids. We report a pilot safety/feasibility study of ultrasound-activated muS with systemic tissue plasminogen activator (tPA). METHODS Stroke subjects treated within 3 hours had abnormal Thrombolysis in Brain Ischemia (TIBI) residual flow grades 0 to 3 befor...

Journal: :Advances in Colloid and Interface Science 2021

After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned observed untoward effects to product, development perfluorocarbon (PFC)-based O2 nanoemulsions (“blood substitutes”) has come low. Yet, significant further demonstrations PFC O2-delivery efficacy have continuously been reported, such ...

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