Abstract The interplay between T cells, dendritic cells and keratinocytes is crucial for the development maintenance of inflammation in psoriasis. GADD45 proteins mediate DNA repair different including keratinocytes. In immune system, GADD45a GADD45b regulate function activation both lymphocytes links epigenetic regulation through its demethylase activity. Here, we analyzed expression skin, cir...

AIMS To investigate the effect of tissue preparation on immunostaining and to establish whether there is a standard tissue preparation schedule that allows optimal demonstration of all antigens. METHODS Blocks of tonsil were subjected to variations to a standard fixation, processing, and section preparation schedule. The sections were stained with five antibodies-L26 (CD20), UCHL1 (CD45RO), C...