We report the synthesis of the first 2',3'-diamino substituted uridine derivative with xylo-configuration, its use as starting material for the synthesis of salen-type ligands and the first structurally characterised copper(II) complex thereof.

BACKGROUND There are many nucleoside metal complexes known. According to observations made, only very few of them reveal their central ion to be co-ordinated by the sugar part of their molecules. The regio- and stereosspecific exchange of the hydroxyl groups at the sugar moiety by chelating units improves its complexation ability and should give access to a new class of chiral ligands. RESULT...

background: the vascular function of angiotensin ii-type-2 receptors in adults is controversial. we sought their location and function in mouse aortic rings at young and old mice. materials and methods: male c57bl mice (aged 4 and 14 months) were killed by co2. the descending thoracic aorta was cleaned and dissected into rings. aortic rings were mounted in krebs’ solution at 37 °c and then setu...

The objectives of this study were to measure action potential parameters in enzyme-dissociated, adult rat ventricular myocytes stimulated at 1 Hz, to compare these measurements with those obtained from intact ventricular tissue, and to determine myocyte and tissue responses at stimulus frequencies between 0.1 and 5 Hz. Action potentials were characterized in terms of amplitude, overshoot, resti...

objectives: it is essential for clinicians to have adequate knowledge about root canal configurations; although its morphology varies largely in different ethnicities and even in different individuals with the same ethnic background. the current study aims to review the root canal configurations of mesiobuccal roots of maxillary first molars in an iranian population based on different epidemiol...

For each Dynkin diagram $D$, we define a ''cluster configuration space'' ${\mathcal{M}}_D$ and partial compactification ${\widetilde {\mathcal{M}}}_D$. $D = A_{n-3}$, have ${\mathcal{M}}_{A_{n-3}} {\mathcal{M}}_{0,n}$, the space of $n$ points on ${\mathbb P}^1$, {\mathcal{M}}}_{A_{n-3}}$ was studied in this case by Brown. The {\mathcal{M}}}_D$ is smooth affine algebraic variety with stratificat...

abstract introduction: the human teeth have many anatomical variations and treatment of each tooth is under the influence of its configuration. therefore, recognizing canal configuration is necessary for a correct endo-dontic therapy, and lack of information about canal configuration causes failure in therapy. since one of the most effective factors on canal configuration is race, we planed to ...