In recent years a number of sensitive immunological techniques have been developed to study proteins in biological fluids. The most recently described is that of Minchin Clarke & Freeman (1966) which is a variant of an immunoelectrophoretic method originally described by Ressler (1960) and given the name of crossed immunoelectrophoresis by Laurel1 (1966). It is highly sensitive and by using a c...

Spectra is usually shown as a two-dimensional graph where colors are directly related to signal levels. A great deal of speech recognition work and research takes this type of parameter directly. In this paper we propose to combine typical signal level values with the vectorial components of a Slope matrix containing orientation information on spectra surfaces. This additional information will ...

The automated interpretation of two-dimensional gel electrophoresis images used in protein separation and analysis presents a formidable problem in the detection and characterization of ill-defined spatial objects. We describe in this paper a hierarchical algorithm that provides a robust, high-sensitivity solution to this problem, which can be easily adapted to a variety of experimental situati...

A strain of Treponema pallidum isolated from a homosexually acquired penile chancre in Birmingham in 1979 was serially passaged in rabbits and compared with the Nichols strain. The two strains appeared identical morphologically, and no gross differences were detected on antigenic analysis by two-dimensional immunoelectrophoresis. The Birmingham strain was, however, considerably less virulent fo...

Many algorithms for graph layout have been devised over the last 30 years spanning both the graph drawing and information visualisation communities. This article first reviews the advances made in the field of graph drawing that have then often been applied by the information visualisation community. There then follows a discussion of a range of techniques developed specifically for graph visua...

2DE and 2D-DIGE based proteomics analysis of serum from women with endometriosis revealed several proteins to be dysregulated. A complete list of these proteins along with their mass spectrometry data and subsequent bioinformatics analysis are presented here. The data is related to "Investigation of serum proteome alterations in human endometriosis" by Dutta et al. [1].

We propose novel approach for navigation in the Semantic Web, which visualizes its repositories in two-dimensional graph of resources and their properties. Our view-based navigation helps users more easily understand and learn browsed information space. This decreases users’ effort to find relevant results in similar and related resources in fast-growing web repositories. Although graphs natura...

Patterns of newly synthesized proteins of Vero cells in different growth states were obtained using two-dimensional gel electrophoresis. The 240 most prevalent peptide spots were then compared. Cells in exponential growth and in the stationary phase were found to have patterns of peptide spots characteristic of their state of growth. The transition between these patterns is progressive, and the...

S protein, a plasma glycoprotein with Mr 78,000, has been shown to interfere with the heparin-catalysed inhibition of thrombin by antithrombin III. This interaction was further evaluated in the present study. Native human blood was replaced by either radiolabelled antithrombin III or radiolabelled prothrombin in the reaction mixture, which was incubated at 37 degrees C. At various time interval...

In this report, we describe methods used to analyze the protein composition of sectioned frozen prostatic tissues by two-dimensional gel electrophoresis. Our results show a high degree of homology in two-dimensional electrophoretograms of proteins extracted from frozen sections of malignant prostate glands. Such homology was not apparent in protein patterns of benign hypertrophic prostatic tiss...