Method Primary epithelial cells were isolated from nasal polyps of 24 affected individuals and from the middle turbinates of 9 healthy controls. After a limited culture period RNA was extracted and the expression profile determined using Human Genome U133 Plus 2.0 Genechip Array (Affymetrix inc., Santa Clara, CA, USA). Supernatants collected from the epithelial cells and immunohistochemistry on...

Moisturizing and keeping clean the air that moves through the nose and get into the lungs are the core responsibilities of the turbinates in human body and respiratory system. In certain situations, inflammatory reaction of tubinates is the first sign that they come across an allergenic substance which can lead to inflammation of them but in real life having such turbinates is not quite as harm...

BACKGROUND The decision to resect the middle turbinate (MT) during functional endoscopic sinus surgery is controversial. Although there have been a variety of studies that examined the functional outcome related to this maneuver, very few studies evaluated the potential for complications, in particular, epistaxis. OBJECTIVE We sought to determine if resection of the MT during functional endos...

OBJECTIVES The pathogenesis of sinonasal polyposis remains unclear, in spite of several investigative approaches. Antrochoanal polyps, a subgroup of sinonasal polyposis along with allergic- and chronic-inflammatory nasal polyps, mostly originate from the maxillary sinus and develop as a unilateral, pedunculated mass towards the nasopharynx. The human papillomavirus (HPV) is discussed as a possi...

OBJECTIVES The objective of this study is to determine if acoustic rhinometry (AR) can predict the outcome of radiofrequency ablation (RFA) of the inferior turbinates. PATIENTS AND METHODS Preoperative AR measurements of 19 subjects undergoing inferior turbinate RFA were analyzed before and after decongestant. The average total percentage change in cross sectional area (CSA) 1 and in total vo...

Our nose, paranasal sinuses, as well as the throat (pharynx) are part of the upper respiratory tract, which consists of two parts. Anatomically, the external and internal parts of the nose can be illustrated. The first consists of nasal bones and nasal cartilages and the internal nose is formed by the nasal cavity and the nasal concha also known as turbinates (choanae), are separated by the nas...