introduction: numerous studies have investigated the prevalence, incidence and clinical manifestations of gastrointestinal stromal tumors (gists). however, little is known about gists in iran. this pioneer study focuses on description of 36 patients with gists in iran. methods: a database was created for 36 patients suffering from gist who were treated in loghman medical center and tehran cance...

phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. while the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors greater than ten centimetres in diameter – the giant phyllodes tumor. we report a case of giant breast tumors and discuss the techniques utilized for pre-operat...

conclusions the authors emphasize on the rarity of this pathology among children, its clinical polymorphism, the necessity of a rapid diagnosis, and an appropriate treatment to avoid complications and recurrence of the tumor. introduction right atrial myxoma is a rare disease among children and its clinical presentation is not specific. case presentation we reported a four-year-old girl with ex...

background: ovarian masses represent a range of pathology from benign cyst to highly aggressive malignant tumors. it has been estimated that gynecologic malignancy account for approximately 2% of all types of cancer in children, 60-70% of these lesions arise in the ovary.  methods: all ovarian masses which were resected or biopsied in mofid children's hospital from 2002 to 2012 were review...

the liver is an organ at risk (oar) in radiotherapy of thoracic and abdominal tumors such as gastric, distal esophagus, lower lung and breast, bile duct, pancreas and whole abdomen. in this study the alteration in liver functional tests (lft) of these patients during radiotherapy was investigated. to that end, the level of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), ...

background: triple-negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare them with other studies. subjects a...

benign fibrous histiocytoma is a rare tumor of nose and paranasal sinuses that originates from histiocytes. ‎‎the main symptoms of patients are nasal obstruction and nasal mass. ‎our patient was presented with chief complaints of nasal obstruction and rhinorrhea non responsive to antibiotic treatment. in computed tomography scan a giant mass in left maxillary sinus and ipsilateral nasal cavity ...

introduction: triple negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare it with other studies. method: be...

chemotherapy research highly prioritizes overcoming the multidrug resistance (mdr) in human tumors. liposomal formulation of fluoxetine, as a fourth generation chemosensitizer, was constructed and characterized for percent entrapment, release profile, morphology, particle size, zeta potential and stability. liposomes were prepared using different active loading techniques. the influence of diff...

background: despite the relative success of surgical resection followed by proton, proton/photon, or conventional radiotherapy in terms of recurrence-free survival, chordomas are still associated with a high rate of recurrence. to our knowledge there are only very few reported cases of this rare tumor detected by f-18 fdg-pet. materials and methods: in this case we show the significance of f-18...