Background & Objective: The Physalis alkekengi is a herbaceous plant belonging to Solanaceae family. According to research, this plant can help inhibit cancer cell growth. Materials & Methods: In this study, the extract of Physalis alkekengi was used to suppress angiogenesis in Balb/c mice. First, the MC4L2 cells were injected in the mice breastbone and the tumor began to grow in this area, th...

We consider a free boundary tumor model under the presence of angiogenesis and time delays in process proliferation, which cell location is incorporated. It assumed that attracts blood vessels at rate proportional to $\alpha$, parameter $\mu$ `aggressiveness' tumor. In this paper, we first prove there exists unique radially symmetric stationary solution $\left(\sigma_{*}, p_{*}, R_{*}\right)$ f...

retinoblastoma is a retinal malignant tumor that occurs in early childhood. the annual incidence of retinoblastoma is approximately one per 14 000 live births. 250 to 300 new cases are reported in the united states each year. it develops due to inactivation of both alleles of the retinoblastoma susceptibility (rb1) gene. all hereditary cases (55%) are with bilateral and multifocal lesions, but ...

Purpose: Previous studies have demonstrated a negative correlation between prostate volume and biopsy yield. By decreasing prostate volume, 5α-reductase inhibitors may enhance cancer detection, which may explain the greater detection of high-grade tumors in the finasteride arm of the Prostate Cancer Prevention Trial (PCPT). Materials and Methods: A mathematical model was constructed analyzing t...