Fluoroscopy is currently used in treatment planning for patients undergoing radiation therapy for lung and abdominal tumors. Radiation oncologists seek to maximize the radiation the tumor receives, and minimize the amount delivered to the surrounding tissues, a task made difficult by movement caused by the breathing of the patient. A model of the tumor motion could greatly improve dose calculat...

To achieve a better therapeutic effect and suppress side effects for lung cancer treatments, latency involved in current radiotherapy devices is aimed to be compensated for improving accuracy of continuous (not gating) irradiation to a respiratory moving tumor. A novel prediction method of lung tumor motion is developed for compensating the latency. An essential core of the method is to extract...

Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) has been limitedly used for orthotopic pancreatic tumor xenografts due to severe respiratory motion artifact in the abdominal area. Orthotopic tumor models offer advantages over subcutaneous ones, because those can reflect the primary tumor microenvironment affecting blood supply, neovascularization, and tumor cell invasion. We have...

Vestibular Schwannoma forms in Schwann cells which cover the vestibular nerve, often internal auditory canal. Symptoms were likely present before excision of tumor. After tumor, symptoms may include, hearing defects, tinnitus, facial muscle abnormalities, headache, and balance impairments. This case report is a female patient with schwannoma, who had few above-mentioned after surgery. Her physi...

It is important to monitor tumor movement during radiotherapy. Respiration-induced motion affects tumors in the thorax and abdomen (in particular, those located in the lung region). For image-guided radiotherapy (IGRT) systems, it is desirable to minimize imaging dose, so external surrogates are used to infer the internal tumor motion between image acquisitions. This process relies on consisten...

Background and purpose Respiratory motion during proton therapy can severely degrade dose distributions, particularly due to interplay effects when using pencil beam scanning. Combined rescanning gating treatments for moving tumors mitigates degradation, but at the cost of increased treatment delivery time. The objective this study was identify time efficiency these degradation-motion mitigatio...