OBJECTIVE Homocysteine is a sex-related risk factor for cardiovascular disease but the reason for dimorphism is unclear. It has been hypothesized that fat-free mass is an independent determinant of the circulating homocysteine and methionine concentrations. METHODS The relationship of homocysteine to body composition was investigated in 52 healthy middle-aged 40-60 year olds. Plasma total hom...

Intrauterine life is a critical period for the development of body fat and metabolic risk. This study investigated associations between birth weight total truncal in adults. To do so, we analyzed data on 10,011 adults participating Brazilian Longitudinal Study Adult Health (ELSA-Brasil) who self-reported as < 2.5kg, 2.5-4.0kg, or > 4.0kg at baseline (2008-2010) underwent bioimpedance next...

BACKGROUND Advances in dual-energy X-ray absorptiometry (DXA) software algorithms have improved the accuracy of this method for body-composition measurement. OBJECTIVE Our objective was to compare the utility of DXA, underwater weighing (UWW), and a multicomponent model (MC) for assessing changes in body composition. DESIGN : Previously sedentary women aged 40-66 y were randomly assigned to...

background: menopause is associated with changes in body composition in postmenopausal women. the aim of this study was to compare the effects of tibolone and continuous combined hormone therapy (ht) on body composition in postmenopausal women. materials and methods: in this randomized clinical trial, 120 menopausal women were randomly selected and divided into three groups. of these, 40 women ...

BACKGROUND Although obesity is widely accepted as a risk factor for knee osteoarthritis, whether weight per se or the specific components of body composition are the major determinants of properties of articular knee cartilage is unclear. OBJECTIVE To examine associations between anthropometric and body composition measures and knee cartilage properties in healthy adults. METHODS 297 health...

Abstract Background Radiographic damage in rheumatoid arthritis (RA) includes erosions and joint space narrowing (JSN). Different mechanisms may underlie their development. The objective of this study was to evaluate predictors these entities separately. Methods Consecutive early RA patients (symptom duration ≤12 months) from a defined area (Malmö, Sweden) recruited during 1995–2005 were invest...