( n — h\ 11 m — h\ I-hi I \l-hj is the number of those elements of S (I, m, n) which contain h fixed elements of E. It is known that condition (1) is not sufficient for S(l, m, n) to exist. It has been proved that no finite projective geometry exists with 7 points on every line. This implies non-existence of 5(2, 7, 43). There arises a problem of finding a necessary and sufficient condition for...

Background\Aim: Quadruple daily administration of proton-pump inhibitor (PPI) therapy achieves potent acid inhibition, and combined with amoxicillin, with its pharmacodynamic and pharmacokinetic characteristics, may be efficient for Helicobacter pylori eradication. We compared the efficacy of two optimized high-dose dual therapies with a bismuth-containing quadruple regimen for treating H. pylo...

Helicobacter pylori (H. pylori) treatment remains a challenge for the clinician, as no available therapy is able to cure the infection in all treated patients. In the last two decades, several antibiotic combinations have been proposed, including triple therapies, bismuth-free therapies (sequential, concomitant, hybrid regimens), and bismuth-based quadruple therapy. Some national and internatio...

Aim. There is a paucity of data on the efficacy of empiric H. pylori treatment after multiple treatment failures. The aim of this study is to examine the efficacy of empiric salvage therapy as a second through sixth line treatment. Methods. In this single gastroenterology center prospective study in Montreal, Canada, patients with failed H. pylori treatment were offered empiric salvage therapy ...

It is shown that a class of Steiner triple systems of order 2−1, obtained by some special switchings from the Hamming Steiner triple system, is embedded into some perfect code, constructed by known switchings of ijk-components from the binary Hamming code. The number of Steiner triple systems of order n and rank less or equal n− log(n + 1) + 2, embedded into perfect binary codes of length n, is...

Quadruple mutations in the Plasmodium falciparum dihydrofolate reductase (PFDHFR) enzyme give rise to the highest level of pyrimethamine resistance leading to treatment failures. We describe here the presence of these quadruple mutations in a majority of P. falciparum isolates from Car Nicobar (Andaman and Nicobar) Island, India. Isolates from the mainland, however, continue to show a prevalenc...

The bismuth-based quadruple regimen has been applied in Helicobacter pylori rescue therapy worldwide. The non-bismuth-based quadruple therapy or "concomitant therapy" is an alternative option in first-line eradication but has not been used in second-line therapy. Discovering a valid regimen for rescue therapy in bismuth-unavailable countries is important. We conducted a randomized controlled tr...

The paper surveys problems, results and methods concerning the coloring of Steiner Triple and Quadruple Systems viewed as mixed hypergraphs. In this setting, two types of conditions are considered: each block of the Steiner system in question has to contain (i) a monochromatic pair of vertices, or, more restrictively, (ii) a triple of vertices that meets precisely two color classes.

In the study, firstly, heat transfer coefficients of windows were calculated according to highest and lowest emissivity values. Secondly, monthly average solar radiation values determined. The coefficient for double, triple quadruple glass windows. Thirdly, in south, north east/west directions five climatic zones multiplied by shading factor, surface area energy factor discrete buildings. Thus,...