Background Maintaining a supersaturated drug solution after the dissolution of the solid dispersions of water insoluble drugs continues to be a great challenge and is important to the oral bioavailability enhancement of hardly soluble drugs. Methods Nimodipine solid dispersions were prepared by hot-melt extrusion and a special tri-block polymer was employed as a co-carrier. The solid dispersi...

This study presents a novel approach for realizing miniaturized multi layer folded tri band micro-strip band pass filter for Wireless Local Area Network (WLAN) and Worldwide interoperatability for Microwave Access (WiMAX) applications. The proposed filter consists of a pair of folded hairpin stepped impedance resonators and pair of open loop resonators to achieve tri-band performance. The size ...

BACKGROUND Elevated concentrations of plasma total homocysteine (tHcy) and serum total cholesterol are risk factors for ischemic heart disease (IHD). Previous studies showed that the consumption of very high doses of unfiltered coffee increases tHcy and total cholesterol. OBJECTIVE A prospective intervention study was performed to assess the effects of coffee consumption on the concentrations...

Collecting lymphatics were obtained from human thigh fat for light microscopy and tridimensional reconstruction at time of operation for varicose veins. No patient had lymphedema and routine sections showed no inflammation or notable pathologic alteration of the surrounding soft tissue. Abundant vasa vasorum was observed around the musculature of superficial collecting lymphatics of human thigh...

The classification performance of the learner is weakened when unlabeled examples are mislabeled during co-training process. A semisupervised co-training algorithm based on assisted learning (AR-Tri-training) was proposed. Firstly, the assisted learning strategy was presented, which is combined with rich information strategy for designing the assisted learner. Secondly, the evaluation factor wa...

Visual recognition requires rich representations that span levels from low to high, scales from small to large, and resolutions from fine to coarse. Even with the depth of features in a convolutional network, a layer in isolation is not enough: compounding and aggregating these representations improves inference of what and where. Architectural efforts are exploring many dimensions for network ...

Abstract In this paper a fitted second-order finite difference method is presented for solving singularly perturbed two-point boundary value problems with the boundary layer at both end (left and right) points. We have introduced a fitting factor in second-order tri-diagonal finite difference scheme and it is obtained from the theory of singular perturbations. The efficient Thomas algorithm is ...