BACKGROUND/AIM The aim of this study was to investigate the therapeutic effect of intestinal trefoil factor (ITF) on necrotizing enterocolitis (NEC) by observing the pathological changes and detecting the protein level differences in Caspase-3, Bax, and Bcl-2 in an NEC neonate rat model. MATERIALS AND METHODS A Wistar rat model of NEC was established and 30 one-day-old neonate Wistar rats wer...

Small- and wide-angle X-ray scattering in solution reveals that chlorophyll (Chl) trefoils self-assemble in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) to yield supramolecular cyclic trimers. Two Chls of each trefoil coordinate to DABCO to form the vertices of the hexagonal structure, while the remaining Chl acts like a substituent on the benzene-like assembly.

Purpose To determine topographic and aberrometric changes after accelerated cross-linking (ACXL; 18 mW/cm2 for 5 min) as measured with OPD Scan III (Nidek Inc., Tokyo, Japan) and their repeatability in patients with mild and moderate keratoconus (KCN). Methods In this prospective study, 25 eyes with mild KCN [Ksteep = 47.24 ± 3.11 diopter (D)] and 20 moderate cases (Ksteep = 52.86 ± 4.39 D) w...

Two experiments were conducted using 2 ruminally and duodenally fistulated steers to determine the digestibility of undegradable intake protein (UIP) of smooth bromegrass (Bromis inermis), birdsfoot trefoil (Lotus coniculatus L.), and heat-treated alfalfa (Medicago sativa) using the mobile nylon bag technique. Undegradable intake protein was determined using neutral detergent insoluble CP at a ...

VEGF165b were significantly higher in patients with SSc than in control subjects. Microvascular endothelial cells (MVECs) isolated from SSc skin expressed and released higher levels of VEGF165b than healthy MVECs. Transforming growth factor1 upregulated the expression of VEGF165b and serine/arginine protein 55 in both SSc and healthy MVECs. In SSc MVECs, VEGF receptor-2 was overexpressed, but i...

Age-associated arterial remodeling involves arterial wall collagen deposition and elastin fragmentation, as well as an increase in arterial pressure. This arterial remodeling is linked to proinflammatory signaling, including transforming growth factor1, monocyte chemoattractant protein 1, and proendothelin 1, activated by extracellular matrix metalloproteinases (MMPs) and orchestrated, in part,...