Mutation in several factors and pathways leads to the development of hepatic cancer i.e. Wnt-β-Catenin Signalling Pathway , activation Insulin-Like Growth Factor (IGF) Pathway, The P13/PTEN/AKT, TP53 Tumour Suppressor Gene. Liver cirrhosis fatty liver predispose normal tissues fibrosis leading cancer. Excessive alcohol intake results inflammation proceeding ultimately carcinoma. Hepatocellular ...
