نتایج جستجو برای: toxicokinetics
تعداد نتایج: 734 فیلتر نتایج به سال:
Abbreviations: BSA: Bovine Serum Albumin; HABA: 4’-Hydroxyazo-Benzene-2-Carboxylic Acid; IQ: Installation Qualification; LIMS: Laboratory Information Management System; MRD: Minimum Required Dilution; OQ: Operational Qualification; PBS: Phosphate-Buffered Saline; PBST: Phosphate-Buffered Saline With 0.01% Tween-20; PEG: Polyethylene Glycol; PK: Pharmacokinetics; PMT: Photomultiplier-Tube; PQ: P...
A proposal has been developed by the Agricultural Chemical Safety Assessment (ACSA) Technical Committee of the ILSI Health and Environmental Sciences Institute (HESI) for an improved approach to assessing the safety of crop protection chemicals. The goal is to ensure that studies are scientifically appropriate and necessary without being redundant, and that tests emphasize toxicological endpoin...
Physicochemical properties of chemicals affect their exposure, toxicokinetics/fate and hazard, and for nanomaterials, the variation of these properties results in a wide variety of materials with potentially different risks. To limit the amount of testing for risk assessment, the information gathering process for nanomaterials needs to be efficient. At the same time, sufficient information to a...
We present a theoretical approach to analysis of toxicokinetics and toxicodynamics using linear systems theory. In our approach, we define two impulse response functions that characterize the kinetic behavior of an environmental agent in the body and the dynamic time-course behavior of its effect on the body. This approach provides a formalism for understanding the relation among exposure, dose...
Although males and females differ both biologically and in their social and power relations throughout their life span, research in environmental and occupational neurotoxicology often ignore sex and/or gender as a characteristic that requires in-depth consideration. The neurotoxicology literature continues to confuse the terms sex (biological attributes) and gender (socially constructed roles ...
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