Early life-stage bioassays have been used as an alternative to short-term adult toxicity tests since they are cost-effective. A single couple can produce hundreds or thousands of embryos and hence can be used as a simple high-throughput approach in toxicity studies. In the present study, zebrafish and sea urchin embryo bioassays were used to test the toxicity of four pharmaceuticals belonging t...

This work investigates the ecotoxicological evaluation of contaminated dredged sediments from French Mediterranean navy harbour (A), commercial port (B) and two composite specimens (C) and (D) coming from the mixture of A and B with other port sediments. The toxicity of elutriates from these sediments is estimated using embryo-toxicity test, Microtox® solid phase test, LuminoTox, phytotoxicity ...

Cyanobacterial blooms are potential health hazards in water supply reservoirs. This paper reports analyses of a cyanobacterial bloom by use of PCR-based methods for direct detection and identification of strains present and determination of their toxigenicity. Serial samples from Malpas Dam, in the New England region of Australia, were analyzed during a prolonged, mixed cyanobacterial bloom in ...

objective: phototoxicity is a kind of dermatitis that is activated by exposure to ultraviolet light following the administration of some drugs or natural products. artemia salina (a. salina) (brine shrimp) has been effectively applied for toxicity testing and is perfect for biological screening of many chemicals for simultaneous evaluation of toxicity and phototoxicity. the objective of this st...

Complementary food was produced from blends of hungry rice (A), pigeon pea (P) and soursop leaves (S). The raw materials were washed with portable water, dried at room temperature, milled hammer mill, fermented for 24 hours 28 ± 2 °C (28 °C), oven-dried 50 12 hours, remilled, sieved to 1 mm pore size packaged in polyethylene bags further analysis. samples the ratio 70:30:0 (sample APS), 65:30:5...

The kinetics of Cu(II) interactions with Susquehanna River (mid-Atlantic, USA) particle suspensions using the copper ion selective electrode (Cu-ISE) method indicated that the concentration of Cu2+ in both the suspension and filtrate was kinetically controlled; the reaction of Cu(II) in the suspension was faster than that in the filtrate. Bioassay tests were performed in continuous flow-through...

The plant A/B toxin ricin represents a heterodimeric glycoprotein belonging to the family of ribosome inactivating proteins, RIPs. Its toxicity towards eukaryotic cells results from the depurination of 28S rRNA due to the N-glycosidic activity of ricin toxin A chain, RTA. Since the extention of RTA by a mammalian-specific endoplasmic reticulum (ER) retention signal (KDEL) significantly increase...