BACKGROUND Allergic conditions are associated with reduced risk of several malignancies. We hypothesized that blood eosinophil count, a marker for allergic disorders, is inversely associated with the risk of colorectal cancer (CRC) in the Atherosclerosis Risk in Communities prospective cohort. To our knowledge, the association between blood eosinophil count and cancer risk has not been investig...

BACKGROUND AND OBJECTIVES The purpose of this study was to evaluate the levels and patterns of total and differential leukocyte counts and their prognostic importance in a cohort of people with and without chronic kidney disease (CKD). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Among 153 veterans without CKD and 267 with, blood leukocyte count was measured at baseline and then repeatedly o...

Elevated leukocyte counts can be a marker of inflammation and infection. The aim of this study was to determine the total leukocyte count and neutrophil-lymphocyte count ratio (NLCR) among Helicobacter pylori-infected patients with peptic ulcer disease (PU) and among asymptomatic subjects (AS) and to evaluate if there is an association between these lab values and the presence of the H. pylori ...

BACKGROUND An increased leukocyte count is an independent risk factor for cardiovascular events, but the association between leukocyte subtype counts and carotid atherosclerosis in patients with diabetes has not been determined. We therefore investigated the correlation between leukocyte subtype counts and intima-media thickness of the common carotid artery (CCA-IMT) in subjects with type 2 dia...

OBJECTIVES Hematological changes are among the most common complications encountered in malaria. This study analyzes and statistically evaluates the hematological changes as a diagnostic test for malaria in patients with acute febrile illness and whether these could guide the physician to institute specific antimalarial treatment. METHODS The present study was an observational study, conducte...

Results A 79-old-year female patient was taking Trimosul (INN: sulfamethoxazole / trimethoprim) 400 mg / 80 mg tablets 2 tablets twice daily from 2012-Jan-05 to 2012Jan-09 for urinary tract infection. On 2012-Jan-09 her total leukocyte count decreased. The suspected drug was withdrawn and her leukocyte count gradually increased. The patient had no previous history of any drug allergy. Laborator...

Background Vancomycin is used for the treatment of resistant staphylococcal and enterococcal infections but is associated with nephrotoxicity. Neutrophil gelatinase-associated lipocalin (NGAL) was recently identified as a sensitive biomarker for acute kidney injury. Here, we aimed to investigate the usefulness of serum NGAL in monitoring patients undergoing vancomycin therapy. Methods A total ...

Reference values for the differential leukocyte count using an automated cytochemical method (Hemalog D) were determined in 1216 healthy children aged 0-16 years. Log-normal distributions for the absolute counts of all the separate cell types and for the total leukocyte counts were determined. For the relative values, a log-normal distribution for the eosinophils and basophils was also establis...