Several signaling pathways control blood cell (hemocyte) development in the Drosophila lymph gland. Mechanisms that modulate and integrate these signals are poorly understood. Here we report that mutation in a conserved endocytic protein Asrij affects signal transmission and causes aberrant lymph gland hematopoiesis. Mammalian Asrij (Ociad1) is expressed in stem cells of the blood vascular syst...

To study the effects of heavy-ion radiosurgery on the hemopoietic function of a silkworm, hemopoietic organs of larvae were locally irradiated with carbon-ion beams, and the changes in the hemocyte density and in the hemocyte function were investigated. When the larvae were irradiated by 50 Gy to 300 Gy carbon ions on the 3rd day of the 4th instar, the hemocyte densities did not change for a wh...

Highlight ResearchWhite shrimp (Litopenaeus vannamei) challenged with IMNV and different stocking densitiesThe water quality parameter values are getting worse along the increase in densityWhite THC value decreased increasing density challenge testThe development of increased an seen from speed percentage appearance clinical symptoms histopathology results AbstractIncreasing affects physiology ...

Drosophila larval hematopoietic organs produce circulating hemocytes that ensure the cellular host defense by recognizing and neutralizing non-self or noxious objects through phagocytosis or encapsulation and melanization. Hematopoietic lineage specification as well as blood cell proliferation and differentiation are tightly controlled. Mutations in genes that regulate lymph gland cell prolifer...

Abstarct Effects of Beauveria bassiana (Bals.-Criv.) spores on immune functions of Glyphodes pyloalis Walker larvae were studied. Total and differential hemocyte counts revealed that infection by B. bassiana caused a dramatic change in hemocyte number. In vivo and in vitro studies demonstrated that increase in time exposure to fungal pathogen resulted in elevated phagocytic activity. Nodules we...