Purpose To investigate the impact of topically administered ophthalmic medications on the onset and severity of bleb-related infections. Methods Data obtained from 104 eyes of 104 patients with bleb-related infections were analyzed. We assigned an infection stage to each eye (stage 1-4) and analyzed the onset severity. Results Steroids and antibiotics were routinely administered to 13 (12.5...

PURPOSE To investigate the short-term efficacy of topical immunosuppressive agents on the survival of cultivated allo-conjunctival equivalents. METHODS Twenty-five eyes of New Zealand white rabbits were included. Temporal conjunctivae were trephined to a diameter of 7.5 mm, and then cultured allo-conjunctival epithelial cells on amniotic membrane were transplanted onto them. Various immunosup...

Introduction Reports of Norwegian or crusted scabies occurring in England are rare (Calnan, 1950). In this condition itching is not a constant symptom, burrows may not be present and the acarus may be found on the head and neck. The acarus is seen within scales and the gross hyperkeratosis may give the skin the appearance of the bark of a tree. Norwegian scabies has been reported in mental defe...

corneal transplantation is the most common and successful form of solid organ transplantation with a 2-year survival rate of over 90% in low risk cases. this high success rate may be due to the immune privileged status of the cornea, acaid (anterior chamber associated immune deviation) induction phenomena and secretion of inhibitory molecules by corneal cells such as il1-ra, il-1a and fas ligan...

We have investigated the efficacy of conditioning skin Langerhans cells (LCs) with agents to promote tolerance and reduce inflammation, with the goal of improving the outcomes of antigen-specific immunotherapy. Topical treatments were assessed ex vivo, using excised human breast skin maintained in organ bath cultures, and in vivo in healthy volunteers by analysing skin biopsies and epidermal bl...

conclusions the individuals should have multidisciplinary approach for the variety of disorders to maintain the appropriate treatment for a better appearance of the patients. case presentation we describe a patient with progressive hemifacial atrophy at right facial side who developed granulomatous uveitis and periferic retinal vasculitis in his left eye. we started topical and systemic steroid...

Posterior sub-Tenon's (PST) injection of steroid has been used for the treatment of uveitis, cystoid macular edema and choroidal neovascularization. It allows high concentration of the drug to be delivered to the posterior segment of the eye via transscleral route with minimal systemic side effects. Triamcinolone acetonide is an aqueous suspension and it maintains a prolonged intraocular steroi...

Background: Patient’s that present with unilateral ocular hypertension can create a diagnostic challenge for the clinician. This observational case reports of a patient who initially presented with unilateral eye pain, whose HSV PCR was negative, however still appeared to respond to anti-viral treatment. The patient had a unilateral intraocular pressure spike that only decreased with addition o...