نتایج جستجو برای: tongue scc

تعداد نتایج: 30490  

2016
KEYVAN SAGHEB KAWE SAGHEB ROMAN RAHIMI-NEDJAT KATHY TAYLOR BILAL AL-NAWAS CHRISTIAN WALTER

Commonly used staging procedures often cannot predict the absence of cervical metastases (CM) in squamous cell carcinomas (SCCs) of the oral cavity. Due to the high incidence of occult CM in numerous N0 cases in the clinic, an elective neck dissection (ND) is performed. The sentinel lymph node biopsy (SNB) is a common concept in the modern surgical therapy of malignancies. The present study eva...

2016
Reza Kaboodkhani Ebrahim Karimi Mohammad Taghi Khorsandi Ashtiani Safoura Kowkabi Mohammad Reza Firouzifar Farzad Yazdani Nasrin Yazdani

INTRODUCTION 90% of the tumors in the head and neck are squamous-cell carcinomas (HNSCC), which have overall 5- year survival rate between 50% -60%. CD44 has been shown to be associated with the prognosis. MATERIALS AND METHODS Biopsy specimens of 51 patients with oral tongue SCC were evaluated by Immunohistochemistry (IHC) for the CD44 antibody. RESULTS There was no significant correlation...

Journal: :Pathology, research and practice 2011
Leila Vazifeh Mostaan Mohammad Taghi Khorsandi Shahriar-Mohammad Reza Sharifian Fatemeh Homee Shandiz Fatemeh Mirashrafi Homa Sabzari Reza Badiee Hasti Borghei Nasrin Yazdani

The aim of this article was to evaluate the expression of E-cadherin and CD44 adhesion molecule in oral tongue squamous cell carcinoma (SCC) since inappropriate expression of adhesion molecules raises the metastatic ability of the tumor cells. Biopsy specimens from 92 patients with tongue SCC were examined for the expression of E-cadherin and CD44 by immunohistochemistry. The relationship of im...

Journal: :International journal of clinical and experimental medicine 2015
Qiang Sun Qigen Fang Shu Guo

PURPOSE There is no consensus regarding the clinical course and prognosis for oral squamous cell carcinoma (SCC) in young patients. In this study, we report our experience with the management of oral squamous cell carcinoma, with a special focus on patients younger than 40 years old. METHODS From 2005 to 2012, all patients were treated for oral (gingiva, the anterior 2/3 of tongue, floor of t...

Journal: :Cancer research 2012
Stephen J Goldie Klaas W Mulder David Wei-Min Tan Scott K Lyons Andrew H Sims Fiona M Watt

New therapeutic strategies are needed to improve treatment of head and neck squamous cell carcinoma (HNSCC), an aggressive tumor with poor survival rates. FRMD4A is a human epidermal stem cell marker implicated previously in epithelial polarity that is upregulated in SCC cells. Here, we report that FRMD4A upregulation occurs in primary human HNSCCs where high expression levels correlate with in...

2015
Chairat Burusapat Weerawut Jarungroongruangchai Mongkon Charoenpitakchai

BACKGROUND Cervical nodal status is one of prognostic factors in head and neck squamous cell carcinoma (HNSCC). The objective of this study was to identify prognostic factors of cervical node status including site and size of primary tumors, presence of lymphovascular invasion, and size of cervical node for appropriate further treatment in HNSCC. METHODS A 5-year retrospective review of patie...

Journal: :The journal of contemporary dental practice 2014
Mojgan Alaeddini Roohollah Barghammadi Nosratollah Eshghyar Shahroo Etemad-Moghadam

AIM The aim of the present study was to analyze data on the characteristics of tongue lesions in dental patients seeking care at the Oral Pathology Service of Tehran University of Medical Sciences, from 1985-2010. MATERIALS AND METHODS Demographic data and histopathologic diagnoses were recorded for all lesions that were documented as occurring on the tongue according to the patient records i...

Journal: :Cancer prevention research 2011
Yizhu Guo Xin Wang Xinyan Zhang Zheng Sun Xiaoxin Chen

Alcohol drinking is a known risk factor for oral cancer in humans. However, previous animal studies on the promoting effect of ethanol on oral carcinogenesis were inconclusive. It is necessary to develop an animal model with which the molecular mechanism of ethanol-related oral carcinogenesis may be elucidated to develop effective prevention strategies. In this study, mice were first treated wi...

Journal: :JAMA otolaryngology-- head & neck surgery 2015
Jessica H Maxwell Lester D R Thompson Margaret S Brandwein-Gensler Bernhard G Weiss Martin Canis Bibianna Purgina Arpan V Prabhu Chi Lai Yongli Shuai William R Carroll Anthony Morlandt Umamaheswar Duvvuri Seungwon Kim Jonas T Johnson Robert L Ferris Raja Seethala Simion I Chiosea

IMPORTANCE Positive margins are associated with poor prognosis among patients with oral tongue squamous cell carcinoma (SCC). However, wide variation exists in the margin sampling technique. OBJECTIVE To determine the effect of the margin sampling technique on local recurrence (LR) in patients with stage I or II oral tongue SCC. DESIGN, SETTING, AND PARTICIPANTS A retrospective study was co...

2016
R Heera T Ayswarya SK Padmakumar P Ismayil

Basaloid squamous cell carcinoma (BSCC) is an aggressive, high-grade, variant of squamous cell carcinoma (SCC), which is uncommon in the oral cavity but slightly more common in the oropharynx. We present two cases of BSCC, one arising in the floor of the mouth and the other arising on the lateral border of the tongue. The diagnosis of this subtype of SCC is important owing to its particular beh...

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