Objective: the accuracy of planning and control artifacts is fundamental for bringing assertiveness to organizational management process. The utility questioned when desired missing. This research aims identify relationship between artifact structure, market assumptions, performance variables with a view adapting profile impact over accuracy. Methods: this quantitative study based on convenienc...

PURPOSE Obesity is one of the most important nutritional disorders in the world which has an obvious relationship with the incidence of metabolic diseases. Obesity prevalence has increased among children and adolescents during recent decades, leading to a rise in Type 2 diabetes mellitus (DM II) prevalence in these two age brackets. Hence, the aim of this study was to assess impaired glucose to...

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results from loss of glucose homeostasis and for which new candidate polymorphisms now rapidly emerge from genome wide association studies. In the Leiden Longevity Study (n=2415), the offspring of long ...

Drug tolerance and withdrawal are insidious responses to drugs of abuse; the first increases drug consumption while the second punishes abstention. Drosophila generate functional tolerance to benzyl alcohol sedation by increasing neural expression of the slo BK-type Ca(2+) activated K(+) channel gene. After drug clearance this change produces a withdrawal phenotype-increased seizure susceptibil...

PURPOSE To investigate the effect of maturation status of bone marrow-derived dendritic cells (BMDCs) on the in vivo immune response to interphotoreceptor retinoid-binding protein (IRBP) 161-180 peptide in experimental autoimmune uveoretinitis (EAU). METHODS Immature and mature BMDCs were generated without or with the stimulation by lipopolysaccharide (LPS), and their mRNA cytokine profile an...

The aims of the study were to determine the impact of temporomandibular disorders (TMD) on self-percieved oral health related quality of life (OHRQoL) and to compare OHRQoL of patients with TMD with a control group. A total of 81 TMD patients participated in a study group and 400 adults served as the control group. The mean OHIP summary scores were computed for all patients with the same diagno...

The aim of this paper is to present the current state of a four-dimensional simulation model of solid tumour growth and response to radiotherapy developed by our group. The most prominent points of the algorithms describing the fundamental biological phenomena involved are outlined. A specific application of the model to a selected clinical case of glioblastoma multiforme is described and compa...

Ears are a new biometric with major advantage in that they appear to maintain their shape with increased age. Any automatic biometric system needs enrolment to extract the target area from the background. In ear biometrics the inputs are often human head profile images. Furthermore ear biometrics is concerned with the effects of partial occlusion mostly caused by hair and earrings. We propose a...

A Pareto optimization study was carried out on a flat pad aerostatic bearing design. Some of the Pareto optimal configurations were then subjected to surface profiling errors including tilt, concavity, convexity and waviness and key performance parameters such as load capacity, stiffness and flow rate determined. From these studies it was concluded that multi-orifice aerostatic flat pad bearing...

INTRODUCTION AND OBJECTIVE Obesity is associated with high rates of dyslipidemia and glucose intolerance. The objective of this study was to evaluate the correlation of anthropometric indices with the lipid and glucose profiles of outpatients. METHODS We performed a cross-sectional study assessing anthropometric and metabolic parameters in a sample of 550 individuals. RESULTS The prevalence...