Osteosarcoma is the most common primary bone tumour in children and adolescents. Accumulating evidence has shown that microRNAs (miRNAs) participate in the development of almost all types of cancer. Here, we investigated the role of miR-224 in the development and progression of osteosarcoma. We demonstrated that miR-224 was down-regulated in osteosarcoma cell lines and tissues. Lower miR-224 le...

We analyze the Grøstl hash function, which is a 2nd-round candidate of the SHA-3 competition. Using the start-from-the-middle variant of the rebound technique, we show collision attacks on the Grøstl-256 hash function reduced to 5 and 6 out of 10 rounds with time complexities 2 and 2, respectively. Furthermore, we demonstrate semi-free-start collision attacks on the Grøstl-224 and -256 hash fun...

Since the beginning of the SHA3 competition, the cryptographic community has seen the emergence of a new kind of primitives: the lightweight cryptographic hash functions. At the time writing this article, two representatives of this category have been published: Quark [7] and PHOTON [18] designed to match RFID constraints. In this paper, we propose a third representative of this category which ...

Background: Better understanding the molecular mechanisms responsible for the genesis and progression of colorectal cancer would help advance the novel therapeutics. miR-224 has been identified to be elevated in colorectal cancer and promote human colorectal cancer cell line SW480 proliferation and invasion. However, the effect of miRNAs on cancer cell proliferation could be significantly chang...

BACKGROUND This study aims to clarify the underlying mechanism for the tumor suppressive function of lnc TUSC7 in chemotherapy resistance of esophageal squamous cell carcinoma (ESCC). METHODS TUSC7, miR-224 and DESC1 expressions in ESCC tissues and cells were detected by qRT-PCR. Protein level of DESC1, EGFR and p-AKT were observed by Western blot. Overall survival was calculated using the Ka...

The Wnt/β-catenin signaling is crucial for the proliferation and migration of breast cancer cells. However, the expression of microRNA-224 (miR-224) in the different types of breast cancers and its role in the Wnt/β-catenin signaling and the proliferation and migration of breast cancer cells are poorly understood. In this study, the levels of miR-224 in different types of breast cancer tissues ...

BACKGROUND In our previous study, we conducted a systematic screening of miRNA to identify potential serum biomarkers for predicting venous metastasis and survival in patients with hepatocellular carcinoma (HCC). miR-224 was one of the differentially expressed miRNAs. This study aimed to confirm whether serum miR-224 level is associated with the presence of venous metastasis and survival. MET...