OBJECTIVES This study aims to evaluate if micro-CT can work as a method for the 3D assessment and analysis of cancellous bone by comparing micro-CT with undecalcified histological sections in OVX rats. METHODS The mandible and tibia of sham, ovariectomised (OVX) and zoledronate-injected ovariectomised (OVX-ZOL) rats were assessed morphometrically. Specimens were scanned by micro-CT. Undecalci...

Investigations into the effect of (re)modeling stimuli on cortical bone in rodents normally rely on analysis of changes in bone mass and architecture at a narrow cross-sectional site. However, it is well established that the effects of axial loading produce site-specific changes throughout bones' structure. Non-mechanical influences (e.g., hormones) can be additional to or oppose locally contro...

This study evaluated the application of laser-induced bone therapy (LIBT) to reduce implant healing time in rat tibia. Twenty 10-week-old female Sprague-Dawlay rats were used. The rats received laser irradiation (laser group) or sham operation (control group) on either side of the tibia. Five days after invasion, titanium implants were inserted in proximal tibia. Five, 10, and 20 days after imp...

this study was performed to evaluate the results of 14 years of application of ilizarov method in treatment of infected non-:union:s of tibia and femur in patients with severe trauma and battlefield wounds. seventeen patients with long bone non:union: (14 were with infected non:union: of tibia out of whom two were associated with tibial bone defects and 3 with infected non-:union: of femur) wer...

Tunnel enlargement can appear after anterior cruciate ligament reconstruction. We investigated the influence of the bone block position of a patellar tendon autograft on the tunnel enlargement in the femur and in the tibia from two aspects. On the one hand, we examined the influence of the tunnel position in respect to the ap-diameter. On the other hand, we examined the influence of the bone bl...

BACKGROUND Infected nonunion of tibia and femur are common in clinical practice, however, the treatment of these diseases has still been a challenge for orthopaedic surgeons. Ilizarov methods can eradicate infection, compensate bone defects and promote the bone union through progressive bone histogenesis. The objective of this systematic review was to review current available studies reporting ...

Recently, 3-T magnetic resonance imaging (MRI) has been introduced for bone imaging. Through higher signal-to-noise ratios, as compared to 1.5-T MRI, it promises to be a more powerful tool for the assessment of cortical and trabecular bone measures. The goal of our study was to compare MRI-derived cortical and trabecular bone measures to quantitative computed tomography (QCT)-derived bone miner...

Methods We present a 14y old girl with polyostotic fibrous dysplasia (right humerus, femur, tibia, skull), precocious puberty and café au lait skin spots, diagnosed as MAS with a confirmed heterozygous c.601C>T mutation of the GNAS1 gene. Due to initial bone pain and continuously increasing bone turnover, the patient was treated with iv bisphosphonates for 4 years. We used pQCT to estimate bone...

Weightless environment due to prolonged Space mission results in decreased mineralisation of the weight bearing bones. Hind limb unweighting (HU) in rats by tail suspension was used to simulate the effect of weightlessness on tibia. Adult male albino rats were divided into two groups as (i) Control (CON, n = 12) and (ii) HU for 15 days (HU, n = 18). After 15 days of HU tibia from all the animal...

BACKGROUND Upper tibia defects ,type3b Gustilo, due to huge size and volume are very difficult to reconstruct; usually several operations are needed for bone and soft tissue defects and the definite one stage reconstruction is yet to be found. OBJECTIVES In this article we reintroduce the rib- latissimus flap as an acceptable method to reconstruct tibia defects in selected cases. MATERIALS ...