PURPOSE The purpose of this study was to determine whether increasing the Ti6Al4V surface oxide negative charge through heat (600℃) or radiofrequency plasma glow discharge (RFGD) pretreatment, with or without a subsequent coating with fibronectin, stimulated osteoblast gene marker expression in the MC3T3 osteoprogenitor cell line. METHODS Quantitative real-time polymerase chain reaction was u...

BACKGROUND High strength porous titanium implants are widely used for the reconstruction of craniofacial defects because of their similar mechanical properties to those of bone. The recent introduction of electron beam melting (EBM) technique allows a direct digitally enabled fabrication of patient specific porous titanium implants, whereas both their in vitro and in vivo biological performance...

Nowadays, salt consumption appears to be drastically above the recommended level in industrialized countries. The health consequences of this overconsumption are heavy since high-salt intake induces cardiovascular disease, kidney dysfunction, and stroke. Moreover, harmful interaction may also occur with orthopaedic devices because overconsumption of salt reinforces the corrosive aspect of biolo...

Lubricating-reinforcing composite coatings were successfully prepared on Ti6Al4V using laser-clad Ti6Al4V/Ni60/Ni-MoS2 mixed powders with different Ni-MoS2 contents (25, 35, and 45 wt.%), their microstructure tribological properties studied. The reinforcing phase TiC, Ti2Ni, the lubricating Ti2SC in situ precipitated while Ti2Ni formed a mosaic coherent structure within above three coatings. In...

Different methods have been evaluated for manufacturing the porous Ti6Al4V alloys according to decreasing stress shielding phenomenon and increasing mechanical compatibility between the metallic components and the host tissue. For this purpose, in this work Ti6Al4V alloy chips were pressed under 400 MPa pressure and then samples were categorized and heated into two groups at 1000 and 1150℃ unde...

A low friction coefficient and high bearing capacity can improve the service life of implants in human body. In this study, we firstly investigate mechanical properties inorganic thermal oxide coatings on titanium alloy (Ti6Al4V). Tribological experiments were performed for different tribo-pairs under uniform conditions. The coating Ti6Al4V formed at 300℃ was found to have excellent tribologica...

There has been limited studies on corrosion behaviour of post-processed electron beam melted (EBM) Ti6Al4V, given that the factors affecting resistance AM Ti6Al4V remain unclear. This paper proposes using heat treatment method to improve pitting EBM Ti6Al4V. Different profiles alter microstructure A clear trend is observed between microhardness and α lath width. As-printed exhibits an inferior ...

Coating titanium alloy implants with titanium nitride (TiN) by the method of Powder Immersion Reaction Assisted Coating (PIRAC) produces a stable layer on their surface. We have examined the ability of the new TiN coating to undergo osseointegration. We implanted TiN-coated and uncoated Ti6Al4V alloy pins into the femora of six-month-old female Wistar rats. SEM after two months showed a bone co...

The susceptibility to the fouling of the NiTi and Ti6Al4V alloys due to the adhesion of microorganisms and the biofilm formation is very significant, especially in the context of an inflammatory state induced by implants contaminated by bacteria, and the implants corrosion stimulated by bacteria. The aim of this work was to examine the differences between the sulphur-oxidizing bacteria (SOB) an...

The purpose of our study was to investigate the antibacterial effect of a spacer (Ti6Al4V) coated with 4x Cu-TiO₂ in an animal model simulating an acute periprosthetic infection by Staphylococcus aureus. Ti6Al4 bolts contaminated with Staphylococcus aureus were implanted into the femoral condyle of rabbits (n = 36) divided into 3 groups. After one week in group 1 (control) the bolts were remove...