Background. Vitiligo is a common skin disorder characterized by macular depigmentation of the skin. The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine disfunction may be involved. Objective. The aim of this study was to determine whether vitiligo is statistically associated with thyroid autoimmunity. Method. In a prospective case-control ...

OBJECTIVE The aim of this study was to determine if pregnancy outcome for women undergoing in vitro fertilization is correlated with pre-conception thyroid-stimulating hormone level. STUDY DESIGN We performed a retrospective cohort study of in vitro fertilization cycles in our private practice with an initial positive serum human chorionic gonadotropin level and thyroid-stimulating hormone le...

AIM To evaluate the clinical usefulness of the thyrotropin releasing hormone (TRH) test and estimation of thyroid autoantibody concentrations in patients with borderline raised thyroid stimulating hormone (TSH). METHODS The records of 34 consecutive patients with persistent borderline increased TSH (4.4-9.9 mU/l) referred to the Medical Investigation Unit were reviewed. The response of patien...

INTRODUCTION In normal conditions follicle-stimulating hormone receptors (FSHR) are expressed in the ovary and the testis. They can also be expressed in gonadal tumors. However, recently we have found FSHR immunostaining in pituitary adenomas, adrenal tumors and neuroendocrine tumors (carcinoids). The aim of this study was to determine whether the same occurs in thyroid tumors. MATERIAL AND M...

Abbreviations: Ab, antibody; ALP, alkaline phospha atrazine conjugated with horseradish peroxidase; CE, c nanotubes; CV, cyclic voltammetry; ELISA, enzyme-linke high-density polyethylene; HRP, horseradish peroxid magnetic beads; NP, nanoparticle; PAP, p-aminoph phosphate; PET, polyethylene terephthalate; POC, point electrode; RT, room temperature; TMB, 3,3′,5,5′-tetramet tetramethylbenzidine di...

Alopecia areata (AA) is a common form of localized, non-scarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis), or total loss of body hair (alopecia universalis). The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine dysfunction may be involved. The aim of this study was to determi...

Background: Rheumatoid arthritis is a systemic inflammatory disease with unknown etiology. There has been considerable debate about the relation between thyroid gland and rheumatic diseases.
 Objective: To assessed prevalence of primary hypothyroidism in patients rheumatoid arthritis, as well association severity arthritis.
 Patients Methods: This study cross-sectional observational i...

OBJECTIVE The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 w...