Patients with IgG4-related disease (IgG4-RD) are diagnosed in Japan by comprehensive or organ-specific diagnostic criteria. To date, criteria have been established for several organs, but not the thyroid. We attempted to establish thyroid (IgG4-RTD) based on IgG4-RD research The Research Program Intractable Diseases from Ministry of Health, Labour and Welfare Japan. These publicly reported memb...

BACKGROUND Thyroid metastases are clinically rare, and usually occur in patients with a history of prior malignancy and when there are metastases elsewhere. Metastases of pancreatic carcinoma to the thyroid are extremely rare, with only three cases reported in the literature. CASE PRESENTATION We report a patient who had a pancreatic carcinoma with metastasis to the thyroid as initial clinica...

A careful pathological examination often reveals the presence of different lesions at various stages of tumor progression and invasion, even in those thyroid glands presenting with solitary nodules. Each thyroid lesion is composed of many different cell types, reflecting the marked heterogeneity of normal thyroid tissue. Among the different chromosome regions altered in thyroid tumors, 7q21 app...

Follicular carcinoma of the thyroid usually presents as nodules with rare cases showing metastasis at diagnosis. But occult follicular carcinoma without any thyroid enlargement and presenting as multiple lytic bone lesions is unusual and relatively rare. Here we report a 66-year old Malay man presenting with occipito-parietal swelling for last two years. He had no thyroid enlargement; no thyroi...

433 A63-YEAR-OLD-WOMAN had right hand weakness accompanying a right neck mass. Examination revealed a large right thyroid mass, bilateral cervical lymphadenopathy, and weakness of the right intrinsic hand muscles and adductor pollicis. Magnetic resonance imaging (MRI) (Fig. 1) revealed a 6.5-cm thyroid mass (A) and a destructive lesion of C7 and T1 with spinal cord compression (B). Thyroid fine...

AIM Ultrasonography and fine-needle aspiration biopsy (FNAB) are the mainstays of diagnosing thyroid cancer accurately and reducing the number of diagnostic lobectomies. No benchmark for diagnostic accuracy has been published in the South African context. This single-institution study addresses this deficit. METHODS The oncology, pathology and surgical records of all patients diagnosed with t...

BACKGROUND Incidental (18)F-FDG uptake in the thyroid on PET-CT examinations represents a diagnostic challenge. The maximal standardized uptake value (SUVmax) is one possible parameter that can help in distinguishing between benign and malignant thyroid PET lesions. PATIENTS AND METHODS We retrospectively evaluated (18)F-FDG PET-CT examinations of 5,911 patients performed at two different med...