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تعداد نتایج: 13666549 فیلتر نتایج به سال:
Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with the toxicity induced by photon absorbers after irradiation with NIR light. The purpose of this study was to determine if MR imaging can detect changes in the MR properties of tumor within several hours of NIR-PIT. A431 cells were injected subcutaneously in t...
PURPOSE Neuromelanin is a dark pigment granule present within certain catecholamine neurons of the human brain. Here, we aimed to clarify the relationship between contrast of neuromelanin-sensitive magnetic resonance imaging (MRI) and MR relaxation times using T1, T2, and T2* mapping of the lower midbrain. METHODS The subjects were 14 healthy volunteers (11 men and 3 women, mean age 29.9 ± 6....
PURPOSE To implement and validate methods for producing calculated coronal T2 maps with complete coverage of the hippocampus and the rest of the brain. METHODS T2 relaxation times were estimated on three occasions for 12 quality assessment test objects with the use of fast spin-echo (FSE) and conventional spin-echo (CSE) sequences. Hippocampal T2 relaxation times were measured in 15 healthy s...
OBJECTIVE Methylphenidate (MPH), the most commonly prescribed drug for attention-deficit/hyperactivity disorder (ADHD), has a short half-life, which necessitates multiple daily doses. The need for multiple doses produces problems with medication administration during school and after-school hours, and therefore with compliance. Previous long-acting stimulants and preparations have shown effects...
BACKGROUND In magnetic resonance (MR) imaging, T1, T2 and T2* relaxation times represent characteristic tissue properties that can be quantified with the help of specific imaging strategies. While there are basic software tools for specific pulse sequences, until now there is no universal software program available to automate pixel-wise mapping of relaxation times from various types of images ...
This study investigated the effects of perturbed cerebral blood flow (CBF) and cerebrovascular reactivity (CR) on relaxation time constant (T2), apparent diffusion coefficient (ADC), fractional anisotropy (FA), and behavioral scores at 1 and 3 hours, 2, 7, and 14 days after traumatic brain injury (TBI) in rats. Open-skull TBI was induced over the left primary forelimb somatosensory cortex (N=8 ...
The effects of substituting dietary protein sources with different levels of Sargassum ilicifolium on growth, survival and body composition of rainbow trout Oncorhynchus mykiss were investigated over the course of a 60 day experiment. A total of 360 juveniles (75±2.8 g) were randomly allotted to four treatment groups including (control: with 100% basal diet (BD); T1: 5% sargassum meal (S...
heuristics are often used to provide solutions for flow shop scheduling problems.the performance of a heuristic is usually judged by comparing solutions and run times on test cases.this investigation proposes an analytical alternative ,called asymptotic convergence ,which tests the convergence of the heuristic to a lower bound as problem size grows. the test is a stronger variation of worst cas...
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