The purpose of this study was to obtain a nicorandil pulsatile release tablet that has a well-regulated release lag time. When nicorandil is used as an antiangina drug, administration time control is important. A pulsatile release tablet is one of the effective approaches to modified release to reduce daily administration frequency. In this study, a pulsatile release tablet of nicorandil was fo...

Physiological characteristics of first order horizontal canal neurons , especially the relationship between their spontaneous activity and response to angular acceleration were studied in 20 albino guinea pigs. The average resting ISI was 48.9ms and this was clearly lower than that in pigmented guinea pigs. The neurons differentiated into three groups according to their CV values. These called ...

Abstract: In this note we consider two cases in the theory of the heat conduction models with three-phase-lag. For each one we propose a suitable Lyapunov function. These functions are relevant tools which allow to study several qualitative properties. We obtain conditions on the material parameters to guarantee the exponential stability of solutions. The spectral analysis complements the resul...

Because of the substantial difference in stiffness between matrix and nanotube in CNT composite, the stress transfer between them controls their mechanical properties. This paper investigates the said issue, analytically and numerically, in axial load using representative volume element (RVE). The analytical model was established based on the modified Cox’s shear lag model with the use of some ...

The dual-phase-lag (DPL) model is applied to study the influence of rotation on a two-dimensional micro-elongated thermoelastic medium problem. Mechanical force along with layer elastic half-space interface and applied. analytic expressions for displacement component, temperature distribution, micro-elongational scalar stress components have been derived represented graphically. has studied in ...

Understanding and modeling of three-phase transient flow in gas-condensate wells play a vital role in designing and optimizing dynamic kill procedure of each well that needs to capture the discontinuities in density, geometry, and velocity of phases but also the effect of temperature on such parameters. In this study, two-phase Advection-Upstream-Splitting-Method (AUSMV) hybrid scheme is extend...

An automatic steering controller was installed on a Case-IH Model 7220 tractor. The primary posture sensor was a kinematic differential GPS. Open loop and closed loop frequency response tests were conducted to evaluate the steering controller dynamics. A double integrator transfer function adequately related vehicle lateral deviation to steering angle within the frequency range of 0.04 Hz to 0....

For frequencies >10 Hz, the vestibuloocular reflex (VOR) has been primarily investigated during passive rotations of the head on the body in humans. These prior studies suggest that eye movements lag head movements, as predicted by a 7-ms delay in the VOR reflex pathways. However, Minor and colleagues recently applied whole-body rotations of frequencies < or =15 Hz in monkeys and found that eye...

T   he completed MCI includes three main channels of interest rate, exchange rate and credit rate. In developing countries such as Iran, this indicator, which contains a credit channel, could be better used to illustrate the country’s monetary condition. This study has been done to calculate this index for the period of 1978–2012. For this purpose, the function of the total economy demand ...