Ezetimibe [1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone] (Zetia; Schering-Plough, Kenilworth, NJ) is the first in a new class of cholesterol-lowering agents known as cholesterol absorption inhibitors. The objective of this study was to identify the isoform(s) of human liver and intestinal UDP-glucuronosyltransferase (UGT) enzymes responsib...

Background: The quadriceps tendon is crucial in allowing knee extension, attaching distally to the patella. While ruptures of are rare, retear can lead muscle atrophy and complex deficits with retraction which may make revision repairs difficult perform. To avoid re-rupture, repair commonly augmented an allograft or autograft, theoretically strengthening repair. Indications: Patients indicated ...

PURPOSE Dyna-ATC is a unilateral external fixator with angulator, lengthener, and translator, which allows for angular correction and compensation of the secondary displacement during angular correction. The purpose of this study is to introduce surgical technique and calculation methods and to evaluate the clinical outcome of angular deformity correction using Dyna-ATC. MATERIALS AND METHODS...

OBJECTIVE To evaluate the clinical and functional results of a surgical treatment of patellar dislocation whose etiology was iatrogenic quadriceps fibrosis in children. MATERIALS AND METHODS A prospective study was undertaken from February 2004 to December 2009. The study included 54 pediatric patients (56 knees) that had developed dislocation of the patella after repeated intramuscular injec...

Abstract Background Sodium glucose cotransporter 2 inhibitors (SGLT2i) have been shown to improve the prognosis of heart failure with preserved ejection fraction (HFpEF) in phase 3 randomized controlled trials (RCTs). However, a granular definition HF was adopted only most recent RCTs (hereafter, RCTs). In earlier studies, which assessed cardiovascular (CV) outcomes patients type diabetes (CV t...

Introduction: The Achilles tendon also named calcaneal tendon, can be subjected to tensile loads up 10 times the body weight. It is located on posterior aspect of lower leg and thickest tendon. This accounts for 20% all large injuries. There discussion which best treatment, among percutaneous repair has risk injuring sural nerve. When a sharp, explosive sudden force exerted rupture or tears occ...

Introduction & Case: A 76 year old woman presented with a painful, valgus right knee measuring 49°. She had a simultaneous peri-articular femoral osteotomy and total knee arthroplasty. Pre and post operative WOMAC and VAS scores were obtained. Results: At 6 weeks, the patient was fully weight bearing without any aids; radiographs demonstrated bony union with good alignment. At one year, the pat...

It is with great pleasure that I call your attention to a milestone in our journal’s history. This issue marks the first of our 21st volume, meaning that Injury Prevention is now 20 years old! The journal will be celebrating a number of ways. Those reading the print edition will already have noted the new cover design. We offered our readers an opportunity to vote, via social media, on one of t...

We report the design and performance of a novel radiofrequency (RF) ion trap mass analyzer, the planar Paul trap, in which a quadrupolar potential distribution is made between two electrode plates. Each plate consists of a series of concentric, lithographically deposited 100-micrometer-wide metal rings, overlaid with a thin resistive layer. To each ring is applied a different RF amplitude, such...

The purpose of this study was to determine whether distraction osteogenesis can be used to treat hypertrophic nonunion associated with angular deformity and shortening after Coventry style high tibial osteotomy. Five consecutive patients were retrospectively reviewed. In all cases, the alignment had collapsed into excessive varus or valgus and leg length discrepancy was present. The leg length ...