Ceftiofur is third generation cephalosporin, broad spectrum antibiotic. It inhibits the cell wall synthesis of bacteria. Ceftiofur is widely used in animals for the treatment of various diseases. Ceftiofur is used against Gram positive and Gram negative bacteria. It has been approved world widely for the treatment of respiratory diseases in sheep, goats, cattle and horses. Ceftiofur sodium phar...

Although mortality and morbidity associated with generalized peritonitis has been brought down markedly, postoperative complications like wound sepsis, intra-abdomlnal collections, paralytic ileus and septicemia do occur in some cases. To minimize such complications different measures have been tried so far, including intraperitoneal lavage with saline solutions and antibiotics. We conducted a ...

1. Cefoperazone is a third generation semi-synthetic cephalosporin with a broad spectrum of activity against the majority of aerobic and anaerobic gram-positive and gram-negative pathogenic bacteria in vitro. Cefoperazone sodium and -dihydrate are used for intramammary treatment of clinical mastitis in lactating cattle. Dose levels used are 250 mg cefoperazone sodium per infected quarter once o...

Resistance of Escherichia coli to third-generation cephalosporin (3GC) in fecal samples representative of French egg production was studied. The susceptibility to cefotaxime of E. coli isolates obtained by culture on nonselective media was determined. Twenty-two nonsusceptible isolates were obtained (7.51%; 95% confidence interval, 4.49 to 10.54%), the majority of which came from young birds. M...

Emergence of multidrug-resistant strains of Shigella is a growing concern across the globe. Third-generation cephalosporins are used for treating infections caused by multidrug-resistant Shigellae. However, resistance to these cephalosporin antibiotics due to extended-spectrum ß-lactamases, has emerged as a new problem. So far extended-spectrum ß-lactamases producing Shigella has not been repor...