The aim of the present study was to examine the effects of ketamine, a dissociative anesthetics, on secretion of catecholamines (CA) secretion evoked by cholinergic stimulation from the perfused model of the isolated rat adrenal gland, and to establish its mechanism of action, and to compare ketamine effect with that of thiopental sodium, which is one of intravenous barbiturate anesthetics. Ket...

Diclofenac sodium is a very common drug used in medical practice for analgesia and is freely available over the counter without any medical prescription. The drug is also the most commonly used or misused by quacks working all over India. Many case reports have been published on upper limb catastrophe of unintentional intra-arterial injection of barbiturates, thiopental sodium, narcotics, and t...

OBJECTIVE The aim of this study was to retrospectively evaluate the intensive care unit treatments applied to obstetrics patients with a diagnosis of posterior reversible encephalopathy syndrome (PRES). MATERIAL AND METHODS The cases of 7 pregnant patients who had been diagnosed with PRES between July 2011 and July 2013 were retrospectively reviewed. The patients' clinical data, brain magneti...

 To determine the neuropharmacological activity of the leaf extract of Croton zambesicus in mice and chicks. The effect of aqueous leaf extract of Croton zambesicus on thiopental sodium – induced sleeping time in mice, on gross locomotor activity (GLA) in 2-day old chicks and effect of extract on apomorphine - induced stereotyped behavior in chicks were evaluated. The a...

A STEROID compound 21-hydroxy-preghalf to one hour prior to anaesthesia. A nane-3, 20-dione sodium succinate 4-litre to 2-litre flow of nitrous-oxide (Viadril) has been used as an intravenous oxygen was administered during the placeanaesthetic. The changes in the electroencephalogram produced by this agent have been observed by Boyan et al. (1955) to be similar to the changes reported by Kierse...

STUDY OBJECTIVE To test whether rapid injection of rocuronium reduces withdrawal movement on injection. DESIGN Randomized, prospective trial. SETTING Operating room in a university hospital. PATIENTS 150 ASA physical status I and II patients aged 18 to 60 years, undergoing general anesthesia. INTERVENTIONS Patients were randomized to three groups. After undergoing anesthesia induction w...

The spinal cord mediates most of the immobilizing action of inhaled anesthetics. In the present study we investigated whether spinal or supraspinal sites mediate the immobilizing action of thiopental in rats. Thiopental was administered IV, intrathecally (IT), intracerebroventricularly (ICV), or simultaneously IT and ICV. Only the IV infusion produced anesthesia, defined as immobility in respon...

OBJECTIVE To compare the effects of propofol and thiopental on haemodynamics, awareness and newborns in pregnant women undergoing elective caesarean section. METHODS Seventy pregnant women were assigned into two equal groups. For anaesthesia induction, 2 mg kg(-1) propofol (Group P) and 5 mg kg(-1) thiopental (Group T) were administered. Maternal haemodynamic parameters and bispectral index (...

BACKGROUND Pain at the site of rocuronium injection is a common side-effect in pediatric patients. This prospective, randomized, double-blind study evaluated the efficacy of a combination of nitrous oxide and lidocaine pretreatment on withdrawal response during rocuronium injection in children. METHODS Sixty six pediatric patients, ages 5 to 12 years, were randomly assigned to two groups. The...